A case of primary pulmonary hypertension associated with carotid sinus hypersensitivity

K. Mitani, S. Hori, T. Yoshikawa, S. Inoue, S. Abe, S. Handa, N. Aikawa, S. Ogawa

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Abstract

A case of primary pulmonary hypertension (PPH) associated with carotid sinus hypersensitivity is described. The patient, a 58-year-old Japanese man with a recent history of frequent episodes of syncope. After physical examination and cardiac catheterization, he was diagnosed as having PPH. Carotid sinus massage was followed by a profound decrease in systolic blood pressure. A beneficial effect on pulmonary hypertension was attained with sublingual nifedipine and intravenous prostaglandin E1. Thereafter, treatment was continued with nifedipine (20 mg/day p.o.) and limaprost (30 ug/day p.o.). Following three months of the medication, pulmonary hypertension was alleviated and nifedipine continued to be effective, but limaprost was not effective in reducing pulmonary hypertension. It was noted that once the pulmonary hypertension had decreased, carotid sinus massage did not induce further decrease of systolic blood pressure. No episode of syncope developed while the patient was under the vasodilator therapy.

Original languageEnglish
Pages (from-to)173-176
Number of pages4
JournalRespiration and Circulation
Volume42
Issue number2
Publication statusPublished - 1994 Jan 1

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Keywords

  • carotid sinus hypersensitivity
  • primary pulmonary hypertension
  • vasodilator therapy

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Mitani, K., Hori, S., Yoshikawa, T., Inoue, S., Abe, S., Handa, S., Aikawa, N., & Ogawa, S. (1994). A case of primary pulmonary hypertension associated with carotid sinus hypersensitivity. Respiration and Circulation, 42(2), 173-176.