A case of simultaneous double cancers with multiple liver metastases responding to S-1+CPT-11

Toshiro Iizuka, Naoki Hirano, Daisuke Kikuchi, Shu Hoteya, Naohisa Yahagi

Research output: Contribution to journalArticle

Abstract

The patient was a 70-year-old male with advanced cancers of stomach and rectum and multiple metastatic hepatic tumors. No resectability was detected. The origin of metastatic hepatic tumors was unknown, so the combination of S-1 and CPT-11 as a treatment regimen was selected. S-1, 80 mg/m2, was administered on 14 consecutive days followed by a 14-day rest period, and CPT-11, 100 mg/m2, was administered on day 1 and day 15. One cycle was defined as 4 weeks, and cycles were repeated. CR was achieved as long as metastatic hepatic tumors after completion of 5 cycles. When we encounter a case of simultaneous double cancers with metastatic sites which has no respectability, generally speaking, it is difficult to determine the strategy for chemotherapy. This case suggests that the combination of S-1 and CPT-11 may be an effective regimen for the treatment of simultaneous advanced cancers of stomach and rectum with multiple hepatic metastases.

Original languageEnglish
Pages (from-to)139-141
Number of pages3
JournalJapanese Journal of Cancer and Chemotherapy
Volume36
Issue number1
Publication statusPublished - 2009 Jan
Externally publishedYes

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irinotecan
Neoplasm Metastasis
Liver
Rectal Neoplasms
Stomach Neoplasms
Neoplasms
Drug Therapy
Therapeutics

Keywords

  • Liver metastases
  • S-1+CPT-11
  • Simultaneous double cancers

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

A case of simultaneous double cancers with multiple liver metastases responding to S-1+CPT-11. / Iizuka, Toshiro; Hirano, Naoki; Kikuchi, Daisuke; Hoteya, Shu; Yahagi, Naohisa.

In: Japanese Journal of Cancer and Chemotherapy, Vol. 36, No. 1, 01.2009, p. 139-141.

Research output: Contribution to journalArticle

Iizuka, Toshiro ; Hirano, Naoki ; Kikuchi, Daisuke ; Hoteya, Shu ; Yahagi, Naohisa. / A case of simultaneous double cancers with multiple liver metastases responding to S-1+CPT-11. In: Japanese Journal of Cancer and Chemotherapy. 2009 ; Vol. 36, No. 1. pp. 139-141.
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