Abstract
The patient was a 70-year-old male with advanced cancers of stomach and rectum and multiple metastatic hepatic tumors. No resectability was detected. The origin of metastatic hepatic tumors was unknown, so the combination of S-1 and CPT-11 as a treatment regimen was selected. S-1, 80 mg/m2, was administered on 14 consecutive days followed by a 14-day rest period, and CPT-11, 100 mg/m2, was administered on day 1 and day 15. One cycle was defined as 4 weeks, and cycles were repeated. CR was achieved as long as metastatic hepatic tumors after completion of 5 cycles. When we encounter a case of simultaneous double cancers with metastatic sites which has no respectability, generally speaking, it is difficult to determine the strategy for chemotherapy. This case suggests that the combination of S-1 and CPT-11 may be an effective regimen for the treatment of simultaneous advanced cancers of stomach and rectum with multiple hepatic metastases.
| Original language | English |
|---|---|
| Pages (from-to) | 139-141 |
| Number of pages | 3 |
| Journal | Japanese Journal of Cancer and Chemotherapy |
| Volume | 36 |
| Issue number | 1 |
| Publication status | Published - 2009 Jan |
| Externally published | Yes |
Fingerprint
Keywords
- Liver metastases
- S-1+CPT-11
- Simultaneous double cancers
ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
A case of simultaneous double cancers with multiple liver metastases responding to S-1+CPT-11. / Iizuka, Toshiro; Hirano, Naoki; Kikuchi, Daisuke; Hoteya, Shu; Yahagi, Naohisa.
In: Japanese Journal of Cancer and Chemotherapy, Vol. 36, No. 1, 01.2009, p. 139-141.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A case of simultaneous double cancers with multiple liver metastases responding to S-1+CPT-11
AU - Iizuka, Toshiro
AU - Hirano, Naoki
AU - Kikuchi, Daisuke
AU - Hoteya, Shu
AU - Yahagi, Naohisa
PY - 2009/1
Y1 - 2009/1
N2 - The patient was a 70-year-old male with advanced cancers of stomach and rectum and multiple metastatic hepatic tumors. No resectability was detected. The origin of metastatic hepatic tumors was unknown, so the combination of S-1 and CPT-11 as a treatment regimen was selected. S-1, 80 mg/m2, was administered on 14 consecutive days followed by a 14-day rest period, and CPT-11, 100 mg/m2, was administered on day 1 and day 15. One cycle was defined as 4 weeks, and cycles were repeated. CR was achieved as long as metastatic hepatic tumors after completion of 5 cycles. When we encounter a case of simultaneous double cancers with metastatic sites which has no respectability, generally speaking, it is difficult to determine the strategy for chemotherapy. This case suggests that the combination of S-1 and CPT-11 may be an effective regimen for the treatment of simultaneous advanced cancers of stomach and rectum with multiple hepatic metastases.
AB - The patient was a 70-year-old male with advanced cancers of stomach and rectum and multiple metastatic hepatic tumors. No resectability was detected. The origin of metastatic hepatic tumors was unknown, so the combination of S-1 and CPT-11 as a treatment regimen was selected. S-1, 80 mg/m2, was administered on 14 consecutive days followed by a 14-day rest period, and CPT-11, 100 mg/m2, was administered on day 1 and day 15. One cycle was defined as 4 weeks, and cycles were repeated. CR was achieved as long as metastatic hepatic tumors after completion of 5 cycles. When we encounter a case of simultaneous double cancers with metastatic sites which has no respectability, generally speaking, it is difficult to determine the strategy for chemotherapy. This case suggests that the combination of S-1 and CPT-11 may be an effective regimen for the treatment of simultaneous advanced cancers of stomach and rectum with multiple hepatic metastases.
KW - Liver metastases
KW - S-1+CPT-11
KW - Simultaneous double cancers
UR - http://www.scopus.com/inward/record.url?scp=79959837385&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79959837385&partnerID=8YFLogxK
M3 - Article
C2 - 19151581
AN - SCOPUS:79959837385
VL - 36
SP - 139
EP - 141
JO - Japanese Journal of Cancer and Chemotherapy
JF - Japanese Journal of Cancer and Chemotherapy
SN - 0385-0684
IS - 1
ER -