A case of spinal and bulbar muscular atrophy with high-stage and high-gleason score prostate cancer responded to maximal androgen blockade therapy

Takeo Kosaka, Akira Miyajima, Eiji Kikuchi, Shinichi Takahashi, Norihiro Suzuki, Mototsugu Oya

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Spinal and bulbar muscular atrophy is a hereditary motor neuron disease caused by the expansion of CAG triplets in the androgen receptor. Because the length of CAG repeat is inversely related with androgen receptor function, patients with a longer CAG repeat are expected to have a lower incidence of prostate cancer. Here, we report an extremely rare case of highstage prostate cancer in a patient with spinal and bulbar muscular atrophy, which responded to maximal androgen blockade therapy.

Original languageEnglish
Pages (from-to)563-565
Number of pages3
JournalJournal of Andrology
Volume33
Issue number4
DOIs
Publication statusPublished - 2012 Jul

Fingerprint

Atrophic Muscular Disorders
Neoplasm Grading
Androgen Receptors
Androgens
Prostatic Neoplasms
Motor Neuron Disease
Incidence
Therapeutics

ASJC Scopus subject areas

  • Urology
  • Reproductive Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

A case of spinal and bulbar muscular atrophy with high-stage and high-gleason score prostate cancer responded to maximal androgen blockade therapy. / Kosaka, Takeo; Miyajima, Akira; Kikuchi, Eiji; Takahashi, Shinichi; Suzuki, Norihiro; Oya, Mototsugu.

In: Journal of Andrology, Vol. 33, No. 4, 07.2012, p. 563-565.

Research output: Contribution to journalArticle

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