A case of spinal and bulbar muscular atrophy with high-stage and high-gleason score prostate cancer responded to maximal androgen blockade therapy

Takeo Kosaka, Akira Miyajima, Eiji Kikuchi, Shinichi Takahashi, Norihiro Suzuki, Mototsugu Oya

Research output: Contribution to journalArticle

2 Citations (Scopus)


Spinal and bulbar muscular atrophy is a hereditary motor neuron disease caused by the expansion of CAG triplets in the androgen receptor. Because the length of CAG repeat is inversely related with androgen receptor function, patients with a longer CAG repeat are expected to have a lower incidence of prostate cancer. Here, we report an extremely rare case of highstage prostate cancer in a patient with spinal and bulbar muscular atrophy, which responded to maximal androgen blockade therapy.

Original languageEnglish
Pages (from-to)563-565
Number of pages3
JournalJournal of Andrology
Issue number4
Publication statusPublished - 2012 Jul 1


ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Reproductive Medicine
  • Endocrinology
  • Urology

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