A Case Report of Autosomal Dominant Polycystic Kidney Disease Under Peritoneal Dialysis With Cyst Infection and Culture-Positive Peritoneal Fluid

Itaru Yasuda, Kazuhiro Hasegawa, Hirobumi Tokuyama, Naoki Washida, Keisuke Shinozuka, Marie Yasuda, Masaki Ryuzaki, Hidenori Urai, Shu Wakino, Hiroshi Itoh

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Abstract

Background: Cyst infection is a complication sometimes seen in patients with autosomal dominant polycystic kidney disease (ADPKD) and often shows through a positive blood culture. However, there have been no reports of ADPKD patients whose cyst infection propagate to peritoneal fluid leading to positive peritoneal fluid culture. Case presentation: A 74-year-old Japanese man with ADPKD under peritoneal dialysis (PD) was presented with left flank pain, fever, and chills at our hospital. He did not show any symptoms or signs suggestive of peritonitis. There were no elevated cell counts or polymorphonuclear leucocytes in his PD fluid. There were some complicated cysts found in computed tomography and magnetic resonance imaging examinations. We clinically diagnosed him as having a renal cyst infection rather than PD-related peritonitis. We initiated treatment by administering ceftriaxone with an immediate favorable response. As the possibility of accompanying prostatitis still remained, we switched to intravenous levofloxacin on the second day. On the 10th day, Helicobacter cinaedi was detected in 2 sets of blood culture as well as in PD fluid. We switched back to ceftriaxone and this treatment was entirely successful. Conclusions: This is the first report of H cinaedi cyst infection which propagates to peritoneal fluid in a patient with ADPKD.

Original languageEnglish
JournalClinical Medicine Insights: Case Reports
Volume12
DOIs
Publication statusPublished - 2019 Apr 1

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Autosomal Dominant Polycystic Kidney
Ascitic Fluid
Peritoneal Dialysis
Cysts
Infection
Ceftriaxone
Peritonitis
Helicobacter
Flank Pain
Chills
Prostatitis
Levofloxacin
Signs and Symptoms
Neutrophils
Fever
Cell Count
Tomography
Magnetic Resonance Imaging
Kidney
Therapeutics

Keywords

  • ADPKD
  • cyst infection
  • Helicobacter cinaedi
  • peritoneal dialysis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A Case Report of Autosomal Dominant Polycystic Kidney Disease Under Peritoneal Dialysis With Cyst Infection and Culture-Positive Peritoneal Fluid. / Yasuda, Itaru; Hasegawa, Kazuhiro; Tokuyama, Hirobumi; Washida, Naoki; Shinozuka, Keisuke; Yasuda, Marie; Ryuzaki, Masaki; Urai, Hidenori; Wakino, Shu; Itoh, Hiroshi.

In: Clinical Medicine Insights: Case Reports, Vol. 12, 01.04.2019.

Research output: Contribution to journalArticle

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