A case report of coronavirus disease-2019-induced acute asthma exacerbation in an obese patient

Hisashi Sasaki, Jun Miyata, Ai Kobayashi, Shuichi Kawano, Akihiko Kawana

Research output: Contribution to journalArticlepeer-review

Abstract

The coronavirus disease-2019 (COVID-19) has spread worldwide. Previous studies indicated a low prevalence of COVID-19 induced acute exacerbations of asthma. We present a 39-year-old-male obese asthmatic case who experienced acute asthma exacerbation during COVID-19. On day 8 of infection, his cough and dyspnea worsened with hypoxia and wheezing. Laboratory test results revealed elevated interleukin-6 (IL-6) and total immunoglobulin E (IgE) levels without eosinophilia. Two months since the onset, hypoxia disappeared with decreased IL-6 and IgE levels. Our case suggested that obesity and high serum IL-6 and IgE levels may have contributed to atypical asthma exacerbation in COVID-19.

Original languageEnglish
Article numbere0979
JournalRespirology Case Reports
Volume10
Issue number7
DOIs
Publication statusPublished - 2022 Jul
Externally publishedYes

Keywords

  • asthma
  • COVID-19
  • immunoglobulin E
  • interleukin-6
  • obesity

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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