A case report of coronavirus disease-2019-induced acute asthma exacerbation in an obese patient

Hisashi Sasaki; Jun Miyata; Ai Kobayashi; Shuichi Kawano; Akihiko Kawana

doi:10.1002/rcr2.979

A case report of coronavirus disease-2019-induced acute asthma exacerbation in an obese patient

Hisashi Sasaki, Jun Miyata, Ai Kobayashi, Shuichi Kawano, Akihiko Kawana

Research output: Contribution to journal › Article › peer-review

Abstract

The coronavirus disease-2019 (COVID-19) has spread worldwide. Previous studies indicated a low prevalence of COVID-19 induced acute exacerbations of asthma. We present a 39-year-old-male obese asthmatic case who experienced acute asthma exacerbation during COVID-19. On day 8 of infection, his cough and dyspnea worsened with hypoxia and wheezing. Laboratory test results revealed elevated interleukin-6 (IL-6) and total immunoglobulin E (IgE) levels without eosinophilia. Two months since the onset, hypoxia disappeared with decreased IL-6 and IgE levels. Our case suggested that obesity and high serum IL-6 and IgE levels may have contributed to atypical asthma exacerbation in COVID-19.

Original language	English
Article number	e0979
Journal	Respirology Case Reports
Volume	10
Issue number	7
DOIs	https://doi.org/10.1002/rcr2.979
Publication status	Published - 2022 Jul
Externally published	Yes

Keywords

asthma
COVID-19
immunoglobulin E
interleukin-6
obesity

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/rcr2.979

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abstract = "The coronavirus disease-2019 (COVID-19) has spread worldwide. Previous studies indicated a low prevalence of COVID-19 induced acute exacerbations of asthma. We present a 39-year-old-male obese asthmatic case who experienced acute asthma exacerbation during COVID-19. On day 8 of infection, his cough and dyspnea worsened with hypoxia and wheezing. Laboratory test results revealed elevated interleukin-6 (IL-6) and total immunoglobulin E (IgE) levels without eosinophilia. Two months since the onset, hypoxia disappeared with decreased IL-6 and IgE levels. Our case suggested that obesity and high serum IL-6 and IgE levels may have contributed to atypical asthma exacerbation in COVID-19.",

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AB - The coronavirus disease-2019 (COVID-19) has spread worldwide. Previous studies indicated a low prevalence of COVID-19 induced acute exacerbations of asthma. We present a 39-year-old-male obese asthmatic case who experienced acute asthma exacerbation during COVID-19. On day 8 of infection, his cough and dyspnea worsened with hypoxia and wheezing. Laboratory test results revealed elevated interleukin-6 (IL-6) and total immunoglobulin E (IgE) levels without eosinophilia. Two months since the onset, hypoxia disappeared with decreased IL-6 and IgE levels. Our case suggested that obesity and high serum IL-6 and IgE levels may have contributed to atypical asthma exacerbation in COVID-19.

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A case report of coronavirus disease-2019-induced acute asthma exacerbation in an obese patient

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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