A case report of multiple gastric carcinomas of seven lesions following completely cured metachronous double carcinomas on sgimoid and ascending colon

Naoto Kurihara, Hisashi Shinohara, Hajime Yonekawa, Takao Machimura, Toshiharu Furukawa, Hideki Nishibori, Hideki Tatematsu, Hidejirou Uragami, Yuji Nemoto, Miwako Mukai

Research output: Contribution to journalArticle

Abstract

A 42-year-old woman who had a sigmoidectomy for sigmoid colon carcinoma in 1983 and right hemicolectomy for ascending colon carcinoma in 1989 was admitted with a chief complaint of epigastric discomfort in 1995. She was diagnosed by endoscopy as having two advanced gastric carcinomas. Total gastrectomy with splenectomy and Roux-en Y reconstruction was performed on September 28, 1995. Two lesions of type 3 advanced gastric carcinoma on the anterior and posterior walls of the body, and five lesions of type 0-IIa early gastric carcinoma on the antrum and body were observed independently. The two lesions of type 3 advanced gastric carcinoma were histologically diagnosed as moderately differentiated adenocarcinoma invading the subserosal layer. Three of the five lesions of type 0-IIa early gastric carcinoma were diagnosed as well-differentiated adenocarcinoma invading the mucosal layer and the other two were diagnosed as well-differentiated adenocarcinoma invading submucosal layer, respectively. These lesions of gastric carcinoma were stained positively by immunohistochemical staining for p53 and Ki-67, and were negative for c-erbE-2 and bcl-2. Chronic gastritis with intestinal metaplasia was observed, which was positive for Helicobacter pylori infection. It is important that we establish a high risk group by finding out factors, which may predict future occurrence of multiple cancers.

Original languageEnglish
Pages (from-to)2282-2286
Number of pages5
JournalJapanese Journal of Gastroenterological Surgery
Volume30
Issue number12
Publication statusPublished - 1997
Externally publishedYes

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Ascending Colon
Stomach
Carcinoma
Adenocarcinoma
Metaplasia
Helicobacter Infections
Sigmoid Colon
Gastritis
Splenectomy
Gastrectomy
Helicobacter pylori
Endoscopy
Staining and Labeling

Keywords

  • High risk factor
  • Metachronous cancers
  • Multiple gastric carcinomas

ASJC Scopus subject areas

  • Gastroenterology
  • Surgery

Cite this

A case report of multiple gastric carcinomas of seven lesions following completely cured metachronous double carcinomas on sgimoid and ascending colon. / Kurihara, Naoto; Shinohara, Hisashi; Yonekawa, Hajime; Machimura, Takao; Furukawa, Toshiharu; Nishibori, Hideki; Tatematsu, Hideki; Uragami, Hidejirou; Nemoto, Yuji; Mukai, Miwako.

In: Japanese Journal of Gastroenterological Surgery, Vol. 30, No. 12, 1997, p. 2282-2286.

Research output: Contribution to journalArticle

Kurihara, N, Shinohara, H, Yonekawa, H, Machimura, T, Furukawa, T, Nishibori, H, Tatematsu, H, Uragami, H, Nemoto, Y & Mukai, M 1997, 'A case report of multiple gastric carcinomas of seven lesions following completely cured metachronous double carcinomas on sgimoid and ascending colon', Japanese Journal of Gastroenterological Surgery, vol. 30, no. 12, pp. 2282-2286.
Kurihara, Naoto ; Shinohara, Hisashi ; Yonekawa, Hajime ; Machimura, Takao ; Furukawa, Toshiharu ; Nishibori, Hideki ; Tatematsu, Hideki ; Uragami, Hidejirou ; Nemoto, Yuji ; Mukai, Miwako. / A case report of multiple gastric carcinomas of seven lesions following completely cured metachronous double carcinomas on sgimoid and ascending colon. In: Japanese Journal of Gastroenterological Surgery. 1997 ; Vol. 30, No. 12. pp. 2282-2286.
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