TY - JOUR
T1 - A catalytic asymmetric anti-selective nitroaldol reaction with a neodymium-sodium heterobimetallic complex
AU - Nitabaru, Tatsuya
AU - Kumagai, Naoya
AU - Shibasaki, Masakatsu
N1 - Funding Information:
This work was financially supported by Grant-in-Aid for specially promoted research. N.K. thanks Grant-in-Aid for Young Scientist (B). Financial support from Toray Co Ltd is gratefully acknowledged.
PY - 2008/1/7
Y1 - 2008/1/7
N2 - A catalytic asymmetric anti-selective nitroaldol reaction with a neodymium-sodium heterobimetallic catalyst is described. A readily accessible amide ligand works efficiently as a chiral platform for the Nd/Na heterobimetallic catalyst in the reaction of various aldehydes and nitroethane, affording anti-1,2-nitro alkanols in good diastereo- and enantioselectivity.
AB - A catalytic asymmetric anti-selective nitroaldol reaction with a neodymium-sodium heterobimetallic catalyst is described. A readily accessible amide ligand works efficiently as a chiral platform for the Nd/Na heterobimetallic catalyst in the reaction of various aldehydes and nitroethane, affording anti-1,2-nitro alkanols in good diastereo- and enantioselectivity.
KW - Asymmetric catalysis
KW - Heterobimetallic catalyst
KW - Neodymium
KW - Nitroaldol (Henry) reaction
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U2 - 10.1016/j.tetlet.2007.11.055
DO - 10.1016/j.tetlet.2007.11.055
M3 - Article
AN - SCOPUS:36849023965
SN - 0040-4039
VL - 49
SP - 272
EP - 276
JO - Tetrahedron Letters
JF - Tetrahedron Letters
IS - 2
ER -