A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury

Recommendations on the Role of Baseline Magnetic Resonance Imaging in Clinical Decision Making and Outcome Prediction

Michael G. Fehlings, Allan R. Martin, Lindsay A. Tetreault, Bizhan Aarabi, Paul Anderson, Paul M. Arnold, Darrel Brodke, Anthony S. Burns, Kazuhiro Chiba, Joseph R. Dettori, Julio C. Furlan, Gregory Hawryluk, Langston T. Holly, Susan Howley, Tara Jeji, Sukhvinder Kalsi-Ryan, Mark Kotter, Shekar Kurpad, Brian K. Kwon, Ralph J. Marino & 13 others Eric Massicotte, Geno Merli, James W. Middleton, Hiroaki Nakashima, Narihito Nagoshi, Katherine Palmieri, Anoushka Singh, Andrea C. Skelly, Eve C. Tsai, Alexander Vaccaro, Jefferson R. Wilson, Albert Yee, James S. Harrop

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Introduction: The objective of this guideline is to outline the role of magnetic resonance imaging (MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury (SCI). Methods: A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI. This review focused on longitudinal studies that controlled for baseline neurologic status. A multidisciplinary Guideline Development Group (GDG) used this information, their clinical expertise, and patient input to develop recommendations on the use of MRI for SCI patients. Based on GRADE (Grading of Recommendation, Assessment, Development and Evaluation), a strong recommendation is worded as “we recommend,” whereas a weaker recommendation is indicated by “we suggest.” Results: Based on the limited available evidence and the clinical expertise of the GDG, our recommendations were: (1) “We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention, when feasible, to facilitate improved clinical decision-making” (quality of evidence, very low) and (2) “We suggest that MRI should be performed in adult patients in the acute period following SCI, before or after surgical intervention, to improve prediction of neurologic outcome” (quality of evidence, low). Conclusions: These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI.

Original languageEnglish
Pages (from-to)221S-230S
JournalGlobal Spine Journal
Volume7
Issue number3_supplement
DOIs
Publication statusPublished - 2017 Sep 1

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Practice Management
Spinal Cord Injuries
Practice Guidelines
Magnetic Resonance Imaging
Guidelines
Nervous System
Clinical Decision-Making
Longitudinal Studies

Keywords

  • acute spinal cord injury
  • clinical decision making
  • clinical guideline
  • guideline
  • magnetic resonance imaging
  • outcome prediction
  • spinal cord injury
  • traumatic spinal cord injury

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine
  • Clinical Neurology

Cite this

A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury : Recommendations on the Role of Baseline Magnetic Resonance Imaging in Clinical Decision Making and Outcome Prediction. / Fehlings, Michael G.; Martin, Allan R.; Tetreault, Lindsay A.; Aarabi, Bizhan; Anderson, Paul; Arnold, Paul M.; Brodke, Darrel; Burns, Anthony S.; Chiba, Kazuhiro; Dettori, Joseph R.; Furlan, Julio C.; Hawryluk, Gregory; Holly, Langston T.; Howley, Susan; Jeji, Tara; Kalsi-Ryan, Sukhvinder; Kotter, Mark; Kurpad, Shekar; Kwon, Brian K.; Marino, Ralph J.; Massicotte, Eric; Merli, Geno; Middleton, James W.; Nakashima, Hiroaki; Nagoshi, Narihito; Palmieri, Katherine; Singh, Anoushka; Skelly, Andrea C.; Tsai, Eve C.; Vaccaro, Alexander; Wilson, Jefferson R.; Yee, Albert; Harrop, James S.

In: Global Spine Journal, Vol. 7, No. 3_supplement, 01.09.2017, p. 221S-230S.

Research output: Contribution to journalArticle

Fehlings, MG, Martin, AR, Tetreault, LA, Aarabi, B, Anderson, P, Arnold, PM, Brodke, D, Burns, AS, Chiba, K, Dettori, JR, Furlan, JC, Hawryluk, G, Holly, LT, Howley, S, Jeji, T, Kalsi-Ryan, S, Kotter, M, Kurpad, S, Kwon, BK, Marino, RJ, Massicotte, E, Merli, G, Middleton, JW, Nakashima, H, Nagoshi, N, Palmieri, K, Singh, A, Skelly, AC, Tsai, EC, Vaccaro, A, Wilson, JR, Yee, A & Harrop, JS 2017, 'A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Role of Baseline Magnetic Resonance Imaging in Clinical Decision Making and Outcome Prediction', Global Spine Journal, vol. 7, no. 3_supplement, pp. 221S-230S. https://doi.org/10.1177/2192568217703089
Fehlings, Michael G. ; Martin, Allan R. ; Tetreault, Lindsay A. ; Aarabi, Bizhan ; Anderson, Paul ; Arnold, Paul M. ; Brodke, Darrel ; Burns, Anthony S. ; Chiba, Kazuhiro ; Dettori, Joseph R. ; Furlan, Julio C. ; Hawryluk, Gregory ; Holly, Langston T. ; Howley, Susan ; Jeji, Tara ; Kalsi-Ryan, Sukhvinder ; Kotter, Mark ; Kurpad, Shekar ; Kwon, Brian K. ; Marino, Ralph J. ; Massicotte, Eric ; Merli, Geno ; Middleton, James W. ; Nakashima, Hiroaki ; Nagoshi, Narihito ; Palmieri, Katherine ; Singh, Anoushka ; Skelly, Andrea C. ; Tsai, Eve C. ; Vaccaro, Alexander ; Wilson, Jefferson R. ; Yee, Albert ; Harrop, James S. / A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury : Recommendations on the Role of Baseline Magnetic Resonance Imaging in Clinical Decision Making and Outcome Prediction. In: Global Spine Journal. 2017 ; Vol. 7, No. 3_supplement. pp. 221S-230S.
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abstract = "Introduction: The objective of this guideline is to outline the role of magnetic resonance imaging (MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury (SCI). Methods: A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI. This review focused on longitudinal studies that controlled for baseline neurologic status. A multidisciplinary Guideline Development Group (GDG) used this information, their clinical expertise, and patient input to develop recommendations on the use of MRI for SCI patients. Based on GRADE (Grading of Recommendation, Assessment, Development and Evaluation), a strong recommendation is worded as “we recommend,” whereas a weaker recommendation is indicated by “we suggest.” Results: Based on the limited available evidence and the clinical expertise of the GDG, our recommendations were: (1) “We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention, when feasible, to facilitate improved clinical decision-making” (quality of evidence, very low) and (2) “We suggest that MRI should be performed in adult patients in the acute period following SCI, before or after surgical intervention, to improve prediction of neurologic outcome” (quality of evidence, low). Conclusions: These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI.",
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AU - Martin, Allan R.

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AU - Aarabi, Bizhan

AU - Anderson, Paul

AU - Arnold, Paul M.

AU - Brodke, Darrel

AU - Burns, Anthony S.

AU - Chiba, Kazuhiro

AU - Dettori, Joseph R.

AU - Furlan, Julio C.

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AU - Kurpad, Shekar

AU - Kwon, Brian K.

AU - Marino, Ralph J.

AU - Massicotte, Eric

AU - Merli, Geno

AU - Middleton, James W.

AU - Nakashima, Hiroaki

AU - Nagoshi, Narihito

AU - Palmieri, Katherine

AU - Singh, Anoushka

AU - Skelly, Andrea C.

AU - Tsai, Eve C.

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AU - Wilson, Jefferson R.

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AU - Harrop, James S.

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