A clinical study on cefteram pivoxil in pediatrics

Yoshitake Satoh, Kazuo Ishikawa, Satoshi Iwata, Hironobu Akita, Keisuke Sunakawa

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Abstract

Clinical evaluations of cefteram pivoxil (CFTM-PI, T-2588) were carried out. The obtained results are summarized as follows. 1. Clinical responses to CFTM-PI of 39 patients with pediatric infections were excellent in 16, good in 21, fair in 1 and poor in 1. The overall efficacy rate was 94.9%. 2. Bacteriologically, eradication rates for 39 isolates presumed to be pathogens were evaluated. The eradication rates obtained were 94.1% in 17 strains of Gram-positive cocci, 90.9% in 22 strains of Gram-negative rods. 3. Side effects observed were diarrhea in 2 patients, diarrhea and abdominal pain in 1, erythema and edema in 1. The incidence was 8.7%. An abnormal value found in clinical laboratory tests was eosinophilia in 1 patient. The results suggested that CFTM-PI might be a very useful and safe drug for the treatment of pediatric infections.

Original languageEnglish
Pages (from-to)1780-1790
Number of pages11
Journalthe japanese journal of antibiotics
Volume42
Issue number8
DOIs
Publication statusPublished - 1989 Jan 1

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

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    Satoh, Y., Ishikawa, K., Iwata, S., Akita, H., & Sunakawa, K. (1989). A clinical study on cefteram pivoxil in pediatrics. the japanese journal of antibiotics, 42(8), 1780-1790. https://doi.org/10.11553/antibiotics1968b.42.1780