A Glucan Having Reticuloendothelial System-Potentiating and Anti-complementary Activities from the Tuber of Pinellia ternata

Masashi Tomoda; RyōKo Gonda; Naoko Ōhara; Noriko Shimizu; Chiho Shishido; Yuka Fujiki

doi:10.1248/bpb.17.859

A Glucan Having Reticuloendothelial System-Potentiating and Anti-complementary Activities from the Tuber of Pinellia ternata

Masashi Tomoda, RyōKo Gonda, Naoko Ōhara, Noriko Shimizu, Chiho Shishido, Yuka Fujiki

School of Pharmacy

Research output: Contribution to journal › Article

9 Citations (Scopus)

Abstract

A glucan, called pinellian G, was isolated from the tuber of Pinellia ternata Breit. It was homogeneous on electrophoresis and gel chromatography, and its molecular mass was estimated to be 1.5 x 10⁴. It is composed solely of D-glucose, in addition to a few O-acetyl groups. Methylation analysis, nuclear magnetic resonance and enzymic degradation studies indicated that it is a branched glucan mainly composed of α-l,4-linked D-glucopyranose residues with partially α-l,3-linked units and 4,6-branching points. The glucan showed significant reticuloendothelial system-potentiating activity in a carbon clearance test, as well as pronounced anti-complementary activity.

Original language	English
Pages (from-to)	859-861
Number of pages	3
Journal	Biological and Pharmaceutical Bulletin
Volume	17
Issue number	6
DOIs	https://doi.org/10.1248/bpb.17.859
Publication status	Published - 1994 Jan 1

Keywords

Pinellia ternata
glucan
immunological activity
pinellian G
polysaccharide structure

ASJC Scopus subject areas

Pharmacology
Pharmaceutical Science

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Tomoda, M., Gonda, R., Ōhara, N., Shimizu, N., Shishido, C., & Fujiki, Y. (1994). A Glucan Having Reticuloendothelial System-Potentiating and Anti-complementary Activities from the Tuber of Pinellia ternata. Biological and Pharmaceutical Bulletin, 17(6), 859-861. https://doi.org/10.1248/bpb.17.859

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