A glucan having reticuloendothelial system-potentiating and anti- complementary activities from the tuber of Pinellia ternata

M. Tomoda, R. Gonda, N. Ohara, N. Shimizu, C. Shishido, Y. Fujiki

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A glucan, called pinellian G, was isolated from the tuber of Pinellia ternata BREIT. It was homogeneous on electrophoresis and gel chromatography, and its molecular mass was estimated to be 1.5 x 104. It is composed solely of D-glucose, in addition to a few O-acetyl groups. Methylation analysis, nuclear magnetic resonance and enzymic degradation studies indicated that it is a branched glucan mainly composed of α-1,4-linked D-glucopyranose residues with partially α-1,3-linked units and 4,6-branching points. The glucan showed significant reticuloendothelial system-potentiating activity in a carbon clearance test, as well as pronounced anti-complementary activity.

Original languageEnglish
Pages (from-to)859-861
Number of pages3
JournalBiological and Pharmaceutical Bulletin
Volume17
Issue number6
Publication statusPublished - 1994
Externally publishedYes

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Pinellia
Mononuclear Phagocyte System
Glucans
Methylation
Gel Chromatography
Electrophoresis
Magnetic Resonance Spectroscopy
Carbon
Glucose

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

A glucan having reticuloendothelial system-potentiating and anti- complementary activities from the tuber of Pinellia ternata. / Tomoda, M.; Gonda, R.; Ohara, N.; Shimizu, N.; Shishido, C.; Fujiki, Y.

In: Biological and Pharmaceutical Bulletin, Vol. 17, No. 6, 1994, p. 859-861.

Research output: Contribution to journalArticle

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AU - Shishido, C.

AU - Fujiki, Y.

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