A Glucan Having Reticuloendothelial System-Potentiating and Anti-complementary Activities from the Tuber of Pinellia ternata

Masashi Tomoda, RyōKo Gonda, Naoko Ōhara, Noriko Shimizu, Chiho Shishido, Yuka Fujiki

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A glucan, called pinellian G, was isolated from the tuber of Pinellia ternata Breit. It was homogeneous on electrophoresis and gel chromatography, and its molecular mass was estimated to be 1.5 x 104. It is composed solely of D-glucose, in addition to a few O-acetyl groups. Methylation analysis, nuclear magnetic resonance and enzymic degradation studies indicated that it is a branched glucan mainly composed of α-l,4-linked D-glucopyranose residues with partially α-l,3-linked units and 4,6-branching points. The glucan showed significant reticuloendothelial system-potentiating activity in a carbon clearance test, as well as pronounced anti-complementary activity.

Original languageEnglish
Pages (from-to)859-861
Number of pages3
JournalBiological and Pharmaceutical Bulletin
Volume17
Issue number6
DOIs
Publication statusPublished - 1994 Jan 1

Keywords

  • Pinellia ternata
  • glucan
  • immunological activity
  • pinellian G
  • polysaccharide structure

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science

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