A method of tagging the nuclear fragmentation event induced by 11C for cancer therapy

Koichi Maruyama, Takashi Hanada, Riki Kikumura, Mitsutaka Kanazawa, Toshimi Suda, Kazushige Maeda

Research output: Contribution to journalArticle

Abstract

Heavy ion cancer therapy using energetic 12C ions has been carried out successfully at the Heavy Ion Medical Accelerator in Chiba (HIMAC), Japan. The method has advantages over traditional radiation therapy using an energetic photon beam in two respects: the dose concentration owing to the Bragg peak and high biological effects. The development of a cancer therapy using 11C ions is also currently underway at HIMAC, however, there remains the problem of beam attenuation due to nuclear fragmentation reactions in the body of the patient; this requires modification of the dose calculation for the therapy. To the best of our knowledge, no research on 11C-induced nuclear fragmentation reactions has yet been published. We propose a method of identifying the nuclear fragmentation reaction event induced by the carbon beams using a total-absorption-type target detector, that plays the role of a human phantom, and a system of plastic scintillation counters surrounding the phantom. We have carried out measurements for the carbon beams with the detector system. A portion of the beam energy is lost as escaping fragment particles from the phantom, leading to a decrease in beam intensity. We were able to successfully detect nuclear reaction events on an event-by-event basis.

Original languageEnglish
Pages (from-to)346-350
Number of pages5
JournalIEEE Transactions on Nuclear Science
Volume53
Issue number1
DOIs
Publication statusPublished - 2006 Feb
Externally publishedYes

Fingerprint

Nuclear reactions
marking
therapy
fragmentation
cancer
Heavy ions
heavy ions
Particle accelerators
Detectors
accelerators
Scintillation counters
Carbon
Radiotherapy
Ions
dosage
biological effects
carbon
Dosimetry
detectors
photon beams

Keywords

  • Cancer
  • Ion beams
  • Medical treatment
  • Nuclear fragmentation reaction
  • Nuclear measurement

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Nuclear Energy and Engineering

Cite this

A method of tagging the nuclear fragmentation event induced by 11C for cancer therapy. / Maruyama, Koichi; Hanada, Takashi; Kikumura, Riki; Kanazawa, Mitsutaka; Suda, Toshimi; Maeda, Kazushige.

In: IEEE Transactions on Nuclear Science, Vol. 53, No. 1, 02.2006, p. 346-350.

Research output: Contribution to journalArticle

Maruyama, Koichi ; Hanada, Takashi ; Kikumura, Riki ; Kanazawa, Mitsutaka ; Suda, Toshimi ; Maeda, Kazushige. / A method of tagging the nuclear fragmentation event induced by 11C for cancer therapy. In: IEEE Transactions on Nuclear Science. 2006 ; Vol. 53, No. 1. pp. 346-350.
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