A near-infrared fluorescent calcium probe

A new tool for intracellular multicolour Ca 2+ imaging

Akihiro Matsui, Keitaro Umezawa, Yutaka Shindo, Tomohiko Fujii, Daniel Citterio, Kotaro Oka, Koji Suzuki

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

We report a novel near-infrared fluorescent calcium probe (KFCA), which has good optical properties such as intense NIR fluorescence emission (670 nm, QY: 0.24), excellent ON/OFF ratio (120-fold), and good wavelength-compatibility with visible-light-emissive fluorophores (Fluo-4, DsRed2), and which is applicable for real-time dual-colour intracellular Ca 2+ imaging.

Original languageEnglish
Pages (from-to)10407-10409
Number of pages3
JournalChemical Communications
Volume47
Issue number37
DOIs
Publication statusPublished - 2011 Oct 7

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Fluorophores
Calcium
Optical properties
Fluorescence
Color
Infrared radiation
Imaging techniques
Wavelength
Fluo 4

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

A near-infrared fluorescent calcium probe : A new tool for intracellular multicolour Ca 2+ imaging. / Matsui, Akihiro; Umezawa, Keitaro; Shindo, Yutaka; Fujii, Tomohiko; Citterio, Daniel; Oka, Kotaro; Suzuki, Koji.

In: Chemical Communications, Vol. 47, No. 37, 07.10.2011, p. 10407-10409.

Research output: Contribution to journalArticle

Matsui, Akihiro ; Umezawa, Keitaro ; Shindo, Yutaka ; Fujii, Tomohiko ; Citterio, Daniel ; Oka, Kotaro ; Suzuki, Koji. / A near-infrared fluorescent calcium probe : A new tool for intracellular multicolour Ca 2+ imaging. In: Chemical Communications. 2011 ; Vol. 47, No. 37. pp. 10407-10409.
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