A near-infrared fluorescent calcium probe: A new tool for intracellular multicolour Ca2+ imaging

Akihiro Matsui; Keitaro Umezawa; Yutaka Shindo; Tomohiko Fujii; Daniel Citterio; Kotaro Oka; Koji Suzuki

doi:10.1039/c1cc14045k

A near-infrared fluorescent calcium probe: A new tool for intracellular multicolour Ca²⁺ imaging

Akihiro Matsui, Keitaro Umezawa, Yutaka Shindo, Tomohiko Fujii, Daniel Citterio, Kotaro Oka, Koji Suzuki

Research output: Contribution to journal › Article › peer-review

78 Citations (Scopus)

Abstract

We report a novel near-infrared fluorescent calcium probe (KFCA), which has good optical properties such as intense NIR fluorescence emission (670 nm, QY: 0.24), excellent ON/OFF ratio (120-fold), and good wavelength-compatibility with visible-light-emissive fluorophores (Fluo-4, DsRed2), and which is applicable for real-time dual-colour intracellular Ca²⁺ imaging.

Original language	English
Pages (from-to)	10407-10409
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	37
DOIs	https://doi.org/10.1039/c1cc14045k
Publication status	Published - 2011 Oct 7

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "We report a novel near-infrared fluorescent calcium probe (KFCA), which has good optical properties such as intense NIR fluorescence emission (670 nm, QY: 0.24), excellent ON/OFF ratio (120-fold), and good wavelength-compatibility with visible-light-emissive fluorophores (Fluo-4, DsRed2), and which is applicable for real-time dual-colour intracellular Ca2+ imaging.",

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AU - Matsui, Akihiro

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AU - Shindo, Yutaka

AU - Fujii, Tomohiko

AU - Citterio, Daniel

AU - Oka, Kotaro

AU - Suzuki, Koji

PY - 2011/10/7

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A near-infrared fluorescent calcium probe: A new tool for intracellular multicolour Ca²⁺ imaging

Abstract

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