A new device for delivering drugs into the inner ear

Otoendoscope with microcatheter

Sho Kanzaki, Hideyuki Saito, Yasuhiro Inoue, Kaoru Ogawa

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Objectives: Intratympanic injection (ITI) of drugs into the inner ear is an attractive way to deliver therapy. However, if the round window membrane (RWM) cannot be visualized, adhesions need to be removed first before ITI can be performed. We developed and tested a novel otoendoscopy device that allows visualization of the RWM for the purpose of ITI. Methods: Our otoendoscope consists of a catheter channel for delivering drugs and a suction channel. Results: The novel otoendoscope for inner ear drug delivery has a fine needle with catheter, which can be used to remove or perforate round window niche (RWN) mucosal adhesions. The elliptical shape of the otoendoscope effectively captures the field in the light-guided area, resulting in bright images. Conclusions: Our otoendoscope can be used to apply drugs directly onto the surface of the RWM and to verify the correct placement of an inner ear drug delivery system, ensuring that it is safely in place.

Original languageEnglish
Pages (from-to)208-211
Number of pages4
JournalAuris Nasus Larynx
Volume39
Issue number2
DOIs
Publication statusPublished - 2012 Apr

Fingerprint

Inner Ear
Equipment and Supplies
Pharmaceutical Preparations
Membranes
Catheters
Suction
Drug Delivery Systems
Needles
Light
Intratympanic Injection
Therapeutics

Keywords

  • Catheter
  • Drug delivery system
  • Inner ear
  • Otoendoscope
  • Round window membrane

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Surgery

Cite this

A new device for delivering drugs into the inner ear : Otoendoscope with microcatheter. / Kanzaki, Sho; Saito, Hideyuki; Inoue, Yasuhiro; Ogawa, Kaoru.

In: Auris Nasus Larynx, Vol. 39, No. 2, 04.2012, p. 208-211.

Research output: Contribution to journalArticle

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