A non-invasive thymoma that occurred 29 years after complete resection of a non-invasive thymoma accompanied by a microthymoma

Yoshikane Yamauchi, Mitsutomo Kohno, Tai Hato, Yuichiro Hayashi, Yotaro Izumi, Hiroaki Nomori

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A 55-year-old woman with a 7 cm non-invasive thymoma and myasthenia gravis had been treated by extended thymectomy via median sternotomy 29 years ago. A microscopic 0.15 cm thymoma (microthymoma) was incidentally found in the thymus during surgery. Twenty-nine years later, a 5 cm thymoma developed in the anterior mediastinum and was surgically treated. The non-invasive first thymoma, the microthymoma and the non-invasive third thymoma were all classified as type AB thymomas according to the World Health Organization (WHO) classification and showed extremely similar histological findings. We think the mechanism underlying the local recurrence of non-invasive thymomas would be intrathymic metastasis because of their clinical and pathological features.

Original languageEnglish
Article numberhyq067
Pages (from-to)986-988
Number of pages3
JournalJapanese journal of clinical oncology
Volume40
Issue number10
DOIs
Publication statusPublished - 2010 May 21

Keywords

  • Intrathymic metastasis
  • Local recurrence
  • Microthymoma
  • Multicentric development
  • Thymoma

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

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