A novel blood glucose monitoring system based on an ISFET biosensor and its application to a human 75 g oral glucose tolerance test

N. Ito, A. Saito, S. Miyamoto, S. Shinohara, T. Kuriyama, J. Kimura, T. Arai, M. Kikuchi, S. Kayashima, N. Nagata, O. Takatani

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A novel blood glucose monitoring system was developed by applying an SOS/ISFET (silicon on sapphire/ion-sensitive field-effect transistor) biosensor to an SEF (suction effusion fluid). The effusion rate of the SEF was 11.9 ± 3.7 μlh-1 cm-2 and the measurement was made every 7.5 min. Glucose concentrations measured using SEF showed a good correlation with those measured by using serum with a slight delay of about 10 min. The blood glucose monitoring system was successfully applied to a non-invasive transcutaneous blood glucose monitoring on human 75 g oral glucose tolerance test. This result shows it will enable realization of a portable blood glucose monitoring device and the system will become very useful in medical treatment.

Original languageEnglish
Pages (from-to)488-490
Number of pages3
JournalSensors and Actuators: B. Chemical
Volume1
Issue number1-6
DOIs
Publication statusPublished - 1990 Jan

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry

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    Ito, N., Saito, A., Miyamoto, S., Shinohara, S., Kuriyama, T., Kimura, J., Arai, T., Kikuchi, M., Kayashima, S., Nagata, N., & Takatani, O. (1990). A novel blood glucose monitoring system based on an ISFET biosensor and its application to a human 75 g oral glucose tolerance test. Sensors and Actuators: B. Chemical, 1(1-6), 488-490. https://doi.org/10.1016/0925-4005(90)80256-Y