A novel blood glucose monitoring system based on an ISFET biosensor and its application to a human 75 g oral glucose tolerance test

N. Ito, A. Saito, S. Miyamoto, S. Shinohara, T. Kuriyama, J. Kimura, Tsunenori Arai, M. Kikuchi, S. Kayashima, N. Nagata, O. Takatani

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A novel blood glucose monitoring system was developed by applying an SOS/ISFET (silicon on sapphire/ion-sensitive field-effect transistor) biosensor to an SEF (suction effusion fluid). The effusion rate of the SEF was 11.9 ± 3.7 μlh-1 cm-2 and the measurement was made every 7.5 min. Glucose concentrations measured using SEF showed a good correlation with those measured by using serum with a slight delay of about 10 min. The blood glucose monitoring system was successfully applied to a non-invasive transcutaneous blood glucose monitoring on human 75 g oral glucose tolerance test. This result shows it will enable realization of a portable blood glucose monitoring device and the system will become very useful in medical treatment.

Original languageEnglish
Pages (from-to)488-490
Number of pages3
JournalSensors and Actuators: B. Chemical
Volume1
Issue number1-6
DOIs
Publication statusPublished - 1990
Externally publishedYes

Fingerprint

Ion sensitive field effect transistors
bioinstrumentation
Biosensors
glucose
blood
Glucose
Blood Glucose
Blood
Monitoring
suction
Fluids
Aluminum Oxide
fluids
Silicon
Sapphire
serums
sapphire
field effect transistors
silicon

ASJC Scopus subject areas

  • Analytical Chemistry
  • Electrochemistry
  • Electrical and Electronic Engineering

Cite this

A novel blood glucose monitoring system based on an ISFET biosensor and its application to a human 75 g oral glucose tolerance test. / Ito, N.; Saito, A.; Miyamoto, S.; Shinohara, S.; Kuriyama, T.; Kimura, J.; Arai, Tsunenori; Kikuchi, M.; Kayashima, S.; Nagata, N.; Takatani, O.

In: Sensors and Actuators: B. Chemical, Vol. 1, No. 1-6, 1990, p. 488-490.

Research output: Contribution to journalArticle

Ito, N, Saito, A, Miyamoto, S, Shinohara, S, Kuriyama, T, Kimura, J, Arai, T, Kikuchi, M, Kayashima, S, Nagata, N & Takatani, O 1990, 'A novel blood glucose monitoring system based on an ISFET biosensor and its application to a human 75 g oral glucose tolerance test', Sensors and Actuators: B. Chemical, vol. 1, no. 1-6, pp. 488-490. https://doi.org/10.1016/0925-4005(90)80256-Y
Ito, N. ; Saito, A. ; Miyamoto, S. ; Shinohara, S. ; Kuriyama, T. ; Kimura, J. ; Arai, Tsunenori ; Kikuchi, M. ; Kayashima, S. ; Nagata, N. ; Takatani, O. / A novel blood glucose monitoring system based on an ISFET biosensor and its application to a human 75 g oral glucose tolerance test. In: Sensors and Actuators: B. Chemical. 1990 ; Vol. 1, No. 1-6. pp. 488-490.
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