A novel cyclic lipoundecapeptide, pholipeptin, isolated from Pseudomonas sp.

Hideaki Ui, Toshiaki Miyake, Hironobu Iinuma, Masaya Imoto, Seiko Hattori, Masa Hamada, Tomio Takeuchi, Sumio Umezawa, Kazuo Umezawa

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

An inhibitor of phosphatidylinositol-specific phospholipase C, pholipeptin, was purified from the culture broth of Pseudomonas sp. Structural determination by 2D NMR spectroscopy with addition of a small amount of trifluoroacetic acid revealed that it was a novel cyclic lipodepsipeptide (1) consisting of 11 amino acids and a 3-hydroxydecanoic acid moiety.

Original languageEnglish
Pages (from-to)7479-7480
Number of pages2
JournalTetrahedron Letters
Volume36
Issue number41
DOIs
Publication statusPublished - 1995 Oct 9

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'A novel cyclic lipoundecapeptide, pholipeptin, isolated from Pseudomonas sp.'. Together they form a unique fingerprint.

  • Cite this

    Ui, H., Miyake, T., Iinuma, H., Imoto, M., Hattori, S., Hamada, M., Takeuchi, T., Umezawa, S., & Umezawa, K. (1995). A novel cyclic lipoundecapeptide, pholipeptin, isolated from Pseudomonas sp. Tetrahedron Letters, 36(41), 7479-7480. https://doi.org/10.1016/0040-4039(95)01601-5