A novel feature of microsatellites in plants: A distribution gradient along the direction of transcription

Shigeo Fujimori, Takanori Washio, Kenichi Higo, Yasuhiro Ohtomo, Kazuo Murakami, Kenichi Matsubara, Jun Kawai, Piero Carninci, Yoshihide Hayashizaki, Shoshi Kikuchi, Masaru Tomita

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

A computer-based analysis was conducted to assess the characteristics of microsatellites in transcribed regions of rice and Arabidopsis. In addition, two mammals were simultaneously analyzed for a comparative analysis. Our analyses confirmed a novel plant-specific feature in which there is a gradient in microsatellite density along the direction of transcription. It was also confirmed that pyrimidine-rich microsatellites are found intensively near the transcription start sites, specifically in the two plants, but not in the mammals. Our results suggest that microsatellites located at high frequency in the 5′-flanking regions of plant genes can potentially act as factors in regulating gene expression.

Original languageEnglish
Pages (from-to)17-22
Number of pages6
JournalFEBS Letters
Volume554
Issue number1-2
DOIs
Publication statusPublished - 2003 Nov 6

Fingerprint

Plant Dispersal
Transcription
Microsatellite Repeats
Mammals
Plant Genes
5' Flanking Region
Transcription Initiation Site
Arabidopsis
Gene expression
Genes
Gene Expression
Direction compound

Keywords

  • Full-length cDNA
  • Microsatellite
  • Tandem repeat
  • Transcribed region
  • Transcriptional regulation

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

A novel feature of microsatellites in plants : A distribution gradient along the direction of transcription. / Fujimori, Shigeo; Washio, Takanori; Higo, Kenichi; Ohtomo, Yasuhiro; Murakami, Kazuo; Matsubara, Kenichi; Kawai, Jun; Carninci, Piero; Hayashizaki, Yoshihide; Kikuchi, Shoshi; Tomita, Masaru.

In: FEBS Letters, Vol. 554, No. 1-2, 06.11.2003, p. 17-22.

Research output: Contribution to journalArticle

Fujimori, S, Washio, T, Higo, K, Ohtomo, Y, Murakami, K, Matsubara, K, Kawai, J, Carninci, P, Hayashizaki, Y, Kikuchi, S & Tomita, M 2003, 'A novel feature of microsatellites in plants: A distribution gradient along the direction of transcription', FEBS Letters, vol. 554, no. 1-2, pp. 17-22. https://doi.org/10.1016/S0014-5793(03)01041-X
Fujimori, Shigeo ; Washio, Takanori ; Higo, Kenichi ; Ohtomo, Yasuhiro ; Murakami, Kazuo ; Matsubara, Kenichi ; Kawai, Jun ; Carninci, Piero ; Hayashizaki, Yoshihide ; Kikuchi, Shoshi ; Tomita, Masaru. / A novel feature of microsatellites in plants : A distribution gradient along the direction of transcription. In: FEBS Letters. 2003 ; Vol. 554, No. 1-2. pp. 17-22.
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