Abstract
The glycosylation of inactive glycosyl donors, such as methyl glycosides and 1-hydroxy sugars with nearly stoichiometric amounts of various alcohols (1.1 equiv) in an ionic liquid containing a protic acid (acid-IL) under reduced pressure conditions proceeded effectively to give the corresponding glycosides in good to high yields. Furthermore, the acid-IL could be reused for additional glycosylations without the loss of efficiency.
| Original language | English |
|---|---|
| Pages (from-to) | 6294-6297 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 51 |
| Issue number | 48 |
| DOIs | |
| Publication status | Published - 2010 Dec 1 |
Fingerprint
Keywords
- Glycosylation
- Green chemistry
- Inactive sugar
- Ionic liquids
- Reduced pressure
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery
Cite this
A novel glycosylation of inactive glycosyl donors using an ionic liquid containing a protic acid under reduced pressure conditions. / Kuroiwa, Yasutaka; Sekine, Maiko; Tomono, Satoshi; Takahashi, Daisuke; Toshima, Kazunobu.
In: Tetrahedron Letters, Vol. 51, No. 48, 01.12.2010, p. 6294-6297.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A novel glycosylation of inactive glycosyl donors using an ionic liquid containing a protic acid under reduced pressure conditions
AU - Kuroiwa, Yasutaka
AU - Sekine, Maiko
AU - Tomono, Satoshi
AU - Takahashi, Daisuke
AU - Toshima, Kazunobu
PY - 2010/12/1
Y1 - 2010/12/1
N2 - The glycosylation of inactive glycosyl donors, such as methyl glycosides and 1-hydroxy sugars with nearly stoichiometric amounts of various alcohols (1.1 equiv) in an ionic liquid containing a protic acid (acid-IL) under reduced pressure conditions proceeded effectively to give the corresponding glycosides in good to high yields. Furthermore, the acid-IL could be reused for additional glycosylations without the loss of efficiency.
AB - The glycosylation of inactive glycosyl donors, such as methyl glycosides and 1-hydroxy sugars with nearly stoichiometric amounts of various alcohols (1.1 equiv) in an ionic liquid containing a protic acid (acid-IL) under reduced pressure conditions proceeded effectively to give the corresponding glycosides in good to high yields. Furthermore, the acid-IL could be reused for additional glycosylations without the loss of efficiency.
KW - Glycosylation
KW - Green chemistry
KW - Inactive sugar
KW - Ionic liquids
KW - Reduced pressure
UR - http://www.scopus.com/inward/record.url?scp=78049391243&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78049391243&partnerID=8YFLogxK
U2 - 10.1016/j.tetlet.2010.09.108
DO - 10.1016/j.tetlet.2010.09.108
M3 - Article
AN - SCOPUS:78049391243
VL - 51
SP - 6294
EP - 6297
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 48
ER -