Abstract
The glycosylation of inactive glycosyl donors, such as methyl glycosides and 1-hydroxy sugars with nearly stoichiometric amounts of various alcohols (1.1 equiv) in an ionic liquid containing a protic acid (acid-IL) under reduced pressure conditions proceeded effectively to give the corresponding glycosides in good to high yields. Furthermore, the acid-IL could be reused for additional glycosylations without the loss of efficiency.
Original language | English |
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Pages (from-to) | 6294-6297 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 51 |
Issue number | 48 |
DOIs | |
Publication status | Published - 2010 Dec 1 |
Keywords
- Glycosylation
- Green chemistry
- Inactive sugar
- Ionic liquids
- Reduced pressure
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry