TY - JOUR
T1 - A novel monocyclic dienediyne system
T2 - Synthesis and mode of aromatization
AU - Toshima, Kazunobu
AU - Yanagawa, Koji
AU - Ohta, Kazumi
AU - Kano, Takaaki
AU - Nakata, Masaya
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1994/3/7
Y1 - 1994/3/7
N2 - The novel monocyclic dienediyne 2, which is a simplified analogue of the neocarzinostatin chromophore (1), was synthesized from D-xylitol via conversion of the keto-aldehyde 13 into the highly strained 10-membered ring compound 14 by a simple intramolecular aldol condensation as the key step. The mode of cycloaromatization of 2 by a thiol addition, reminiscent of the chemistry of 1, was also demonstrated.
AB - The novel monocyclic dienediyne 2, which is a simplified analogue of the neocarzinostatin chromophore (1), was synthesized from D-xylitol via conversion of the keto-aldehyde 13 into the highly strained 10-membered ring compound 14 by a simple intramolecular aldol condensation as the key step. The mode of cycloaromatization of 2 by a thiol addition, reminiscent of the chemistry of 1, was also demonstrated.
UR - http://www.scopus.com/inward/record.url?scp=0028293542&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028293542&partnerID=8YFLogxK
U2 - 10.1016/S0040-4039(00)76761-X
DO - 10.1016/S0040-4039(00)76761-X
M3 - Article
AN - SCOPUS:0028293542
VL - 35
SP - 1573
EP - 1576
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 10
ER -