A Novel Neutral Polysaccharide Having Activity on the Reticuloendothelial System from the Root of Glycyrrhiza uralensis

Noriko Shimizu; Masashi Tomoda; Mieko Kanari; Ryoko Gonda; Akemi Satoh; Noriko Satoh

doi:10.1248/cpb.38.3069

A Novel Neutral Polysaccharide Having Activity on the Reticuloendothelial System from the Root of Glycyrrhiza uralensis

Noriko Shimizu, Masashi Tomoda, Mieko Kanari, Ryoko Gonda, Akemi Satoh, Noriko Satoh

School of Pharmacy

Research output: Contribution to journal › Article

20 Citations (Scopus)

Abstract

A neutral polysaccharide, named glycyrrhizan UC, was isolated from the root of Glycyrrhiza uralensis fischer. It was homogeneous on electrophoresis and gel chromatography, and its molecular mass was estimated to be 69000. Glycyrrhizan UC is composed of L-arabinose: D-galactose: D-glucose: L-rhamnose in the molar ratio of 10:30 27:1. Methylation analysis, carbon-13 nuclear magnetic resonance and periodate oxidation studies indicated its structural feature as an arabino-3,6-galacto-glucan type polysaccharide.

Original language	English
Pages (from-to)	3069-3071
Number of pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	38
Issue number	11
DOIs	https://doi.org/10.1248/cpb.38.3069
Publication status	Published - 1990 Jan 1

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Keywords

Glycyrrhiza uralensis
arabinogalactoglucan
glycyrrhizan UC
immunological activity
licorice
polysaccharide structure
reticuloendothelial system
root

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

Cite this

Shimizu, N., Tomoda, M., Kanari, M., Gonda, R., Satoh, A., & Satoh, N. (1990). A Novel Neutral Polysaccharide Having Activity on the Reticuloendothelial System from the Root of Glycyrrhiza uralensis. Chemical and Pharmaceutical Bulletin, 38(11), 3069-3071. https://doi.org/10.1248/cpb.38.3069

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10.1248/cpb.38.3069