A Novel Neutral Polysaccharide Having Activity on the Reticuloendothelial System from the Root of Glycyrrhiza uralensis

Noriko Shimizu, Masashi Tomoda, Mieko Kanari, Ryoko Gonda, Akemi Satoh, Noriko Satoh

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20 Citations (Scopus)

Abstract

A neutral polysaccharide, named glycyrrhizan UC, was isolated from the root of Glycyrrhiza uralensis fischer. It was homogeneous on electrophoresis and gel chromatography, and its molecular mass was estimated to be 69000. Glycyrrhizan UC is composed of L-arabinose: D-galactose: D-glucose: L-rhamnose in the molar ratio of 10:30 27:1. Methylation analysis, carbon-13 nuclear magnetic resonance and periodate oxidation studies indicated its structural feature as an arabino-3,6-galacto-glucan type polysaccharide.

Original languageEnglish
Pages (from-to)3069-3071
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Volume38
Issue number11
DOIs
Publication statusPublished - 1990 Jan 1

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Keywords

  • Glycyrrhiza uralensis
  • arabinogalactoglucan
  • glycyrrhizan UC
  • immunological activity
  • licorice
  • polysaccharide structure
  • reticuloendothelial system
  • root

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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