A "philosophical molecule," hydrogen may overcome senescence and intractable diseases

Shin Ichi Hirano, Yusuke Ichikawa, Ryosuke Kurokawa, Yoshiyasu Takefuji, Fumitake Satoh

Research output: Contribution to journalReview article


It has been revealed that the cause of senescence and diseases is associated with the reactive oxygen species "hydroxyl radicals" (·OH). Senescence and diseases may be overcome as long as we can scavenge •OH mostly produced in mitochondria. It is one and only one "molecular hydrogen" (H2) that can both penetrate into the mitochondria and scavenge the •OH. The H2 in the body can function in disease prevention and recovery. H2 gas is explosive so that a safe hydrogen inhaler has to be developed for home use. We would like to advocate the great use of H2.

Original languageEnglish
Pages (from-to)47-49
Number of pages3
JournalMedical gas research
Issue number1
Publication statusPublished - 2020 Jan 1


  • Amazon
  • Apple
  • Facebook
  • Google
  • hydroxyl radicals
  • mitochondria
  • molecular hydrogen
  • oxidation
  • reactive oxygen species
  • reduction
  • rejuvenation
  • senescence

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Anesthesiology and Pain Medicine

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