A piezoresistive cellular traction force sensor

U. G. Jung, H. Takahashi, T. Kan, K. Matsumoto, I. Shimoyama

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

This paper presents a rigid piezoresistive sensor to measure cellular traction forces. The traction forces on a rigid substrate such as bone (10∼30 [GPa]) are still unknown. Our approach of the traction force measurement is not by an observation [1-4] but by a resistance change of the piezo-resistor due to the deformation of the rigid sensor (spring constant: 900 nN/μm). Because of its high sensitivity with sub-μN resolution, we were able to measure the traction forces on the rigid substrate. The stiffness of the proposed sensor was 10 times larger than that of previous works. We demonstrated that the traction forces generated by fibroblast were 0.7 μN when two cells adhered to the sensor.

Original languageEnglish
Title of host publicationIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Pages927-930
Number of pages4
DOIs
Publication statusPublished - 2013 Apr 2
Externally publishedYes
EventIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 - Taipei, Taiwan, Province of China
Duration: 2013 Jan 202013 Jan 24

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)1084-6999

Other

OtherIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
CountryTaiwan, Province of China
CityTaipei
Period13/1/2013/1/24

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ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Jung, U. G., Takahashi, H., Kan, T., Matsumoto, K., & Shimoyama, I. (2013). A piezoresistive cellular traction force sensor. In IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 (pp. 927-930). [6474396] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2013.6474396