Abstract
Since the intracutaneous reaction tests of injectable antimicrobials were concluded to be ineffective in the prediction of anaphylactic reaction due to these drugs in 2003, it was decided to suspend these reaction tests. However, the materials for intracutaneous reaction tests remain available. We conducted a questionnaire involving 38 pharmaceutical companies that produce intracutaneous reaction test materials. We collected valid responses from 32 companies (a response rate of 91%). In 2009, intracutaneous reaction test materials were available for 93 drug products, although the number of shipments had decreased to 1,630,000. As the reason for continued supply of intracutaneous reaction test materials to clinical facilities, 28 of the 29 companies that responded to the question cited "request from clinical facilities". The pharmaceutical companies received inquiries regarding the methods for predicting anaphylaxis caused by antimicrobials, including the preparation of test solutions, the method for conducting a prick test, and information provided by relevant academic societies and the Ministry of Health, Labour and Welfare. To avoid intracutaneous reaction tests to predict anaphylaxis, and provide effective antimicrobial therapy in clinical practice, it is important for medical professionals including MR and MS as well as medical doctors and pharmacists, to share proper information regarding the method to predict anaphylaxis due to injectable antimicrobials.
| Original language | English |
|---|---|
| Pages (from-to) | 297-300 |
| Number of pages | 4 |
| Journal | Japanese Journal of Chemotherapy |
| Volume | 61 |
| Issue number | 3 |
| Publication status | Published - 2013 May |
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Keywords
- Drug allergy
- Intracutaneous reaction test
- Questionnaire survey
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)
Cite this
A questionnaire survey on the supply of intracutaneous reaction test materials from pharmaceutical companies. / Hori, Seiji; Yamakawa, Yoshihiro; Maezawa, Kayoko; Terajima, Tomoko; Yoshida, Masaki; Kizu, Junko.
In: Japanese Journal of Chemotherapy, Vol. 61, No. 3, 05.2013, p. 297-300.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A questionnaire survey on the supply of intracutaneous reaction test materials from pharmaceutical companies
AU - Hori, Seiji
AU - Yamakawa, Yoshihiro
AU - Maezawa, Kayoko
AU - Terajima, Tomoko
AU - Yoshida, Masaki
AU - Kizu, Junko
PY - 2013/5
Y1 - 2013/5
N2 - Since the intracutaneous reaction tests of injectable antimicrobials were concluded to be ineffective in the prediction of anaphylactic reaction due to these drugs in 2003, it was decided to suspend these reaction tests. However, the materials for intracutaneous reaction tests remain available. We conducted a questionnaire involving 38 pharmaceutical companies that produce intracutaneous reaction test materials. We collected valid responses from 32 companies (a response rate of 91%). In 2009, intracutaneous reaction test materials were available for 93 drug products, although the number of shipments had decreased to 1,630,000. As the reason for continued supply of intracutaneous reaction test materials to clinical facilities, 28 of the 29 companies that responded to the question cited "request from clinical facilities". The pharmaceutical companies received inquiries regarding the methods for predicting anaphylaxis caused by antimicrobials, including the preparation of test solutions, the method for conducting a prick test, and information provided by relevant academic societies and the Ministry of Health, Labour and Welfare. To avoid intracutaneous reaction tests to predict anaphylaxis, and provide effective antimicrobial therapy in clinical practice, it is important for medical professionals including MR and MS as well as medical doctors and pharmacists, to share proper information regarding the method to predict anaphylaxis due to injectable antimicrobials.
AB - Since the intracutaneous reaction tests of injectable antimicrobials were concluded to be ineffective in the prediction of anaphylactic reaction due to these drugs in 2003, it was decided to suspend these reaction tests. However, the materials for intracutaneous reaction tests remain available. We conducted a questionnaire involving 38 pharmaceutical companies that produce intracutaneous reaction test materials. We collected valid responses from 32 companies (a response rate of 91%). In 2009, intracutaneous reaction test materials were available for 93 drug products, although the number of shipments had decreased to 1,630,000. As the reason for continued supply of intracutaneous reaction test materials to clinical facilities, 28 of the 29 companies that responded to the question cited "request from clinical facilities". The pharmaceutical companies received inquiries regarding the methods for predicting anaphylaxis caused by antimicrobials, including the preparation of test solutions, the method for conducting a prick test, and information provided by relevant academic societies and the Ministry of Health, Labour and Welfare. To avoid intracutaneous reaction tests to predict anaphylaxis, and provide effective antimicrobial therapy in clinical practice, it is important for medical professionals including MR and MS as well as medical doctors and pharmacists, to share proper information regarding the method to predict anaphylaxis due to injectable antimicrobials.
KW - Drug allergy
KW - Intracutaneous reaction test
KW - Questionnaire survey
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M3 - Article
AN - SCOPUS:84878394908
VL - 61
SP - 297
EP - 300
JO - Japanese Journal of Chemotherapy
JF - Japanese Journal of Chemotherapy
SN - 1340-7007
IS - 3
ER -