A questionnaire survey on the supply of intracutaneous reaction test materials from pharmaceutical companies

Seiji Hori, Yoshihiro Yamakawa, Kayoko Maezawa, Tomoko Terajima, Masaki Yoshida, Junko Kizu

Research output: Contribution to journalArticle

Abstract

Since the intracutaneous reaction tests of injectable antimicrobials were concluded to be ineffective in the prediction of anaphylactic reaction due to these drugs in 2003, it was decided to suspend these reaction tests. However, the materials for intracutaneous reaction tests remain available. We conducted a questionnaire involving 38 pharmaceutical companies that produce intracutaneous reaction test materials. We collected valid responses from 32 companies (a response rate of 91%). In 2009, intracutaneous reaction test materials were available for 93 drug products, although the number of shipments had decreased to 1,630,000. As the reason for continued supply of intracutaneous reaction test materials to clinical facilities, 28 of the 29 companies that responded to the question cited "request from clinical facilities". The pharmaceutical companies received inquiries regarding the methods for predicting anaphylaxis caused by antimicrobials, including the preparation of test solutions, the method for conducting a prick test, and information provided by relevant academic societies and the Ministry of Health, Labour and Welfare. To avoid intracutaneous reaction tests to predict anaphylaxis, and provide effective antimicrobial therapy in clinical practice, it is important for medical professionals including MR and MS as well as medical doctors and pharmacists, to share proper information regarding the method to predict anaphylaxis due to injectable antimicrobials.

Original languageEnglish
Pages (from-to)297-300
Number of pages4
JournalJapanese Journal of Chemotherapy
Volume61
Issue number3
Publication statusPublished - 2013 May

Fingerprint

Anaphylaxis
Pharmaceutical Preparations
Injections
Pharmacists
Surveys and Questionnaires
Health
Therapeutics

Keywords

  • Drug allergy
  • Intracutaneous reaction test
  • Questionnaire survey

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

Hori, S., Yamakawa, Y., Maezawa, K., Terajima, T., Yoshida, M., & Kizu, J. (2013). A questionnaire survey on the supply of intracutaneous reaction test materials from pharmaceutical companies. Japanese Journal of Chemotherapy, 61(3), 297-300.

A questionnaire survey on the supply of intracutaneous reaction test materials from pharmaceutical companies. / Hori, Seiji; Yamakawa, Yoshihiro; Maezawa, Kayoko; Terajima, Tomoko; Yoshida, Masaki; Kizu, Junko.

In: Japanese Journal of Chemotherapy, Vol. 61, No. 3, 05.2013, p. 297-300.

Research output: Contribution to journalArticle

Hori, S, Yamakawa, Y, Maezawa, K, Terajima, T, Yoshida, M & Kizu, J 2013, 'A questionnaire survey on the supply of intracutaneous reaction test materials from pharmaceutical companies', Japanese Journal of Chemotherapy, vol. 61, no. 3, pp. 297-300.
Hori, Seiji ; Yamakawa, Yoshihiro ; Maezawa, Kayoko ; Terajima, Tomoko ; Yoshida, Masaki ; Kizu, Junko. / A questionnaire survey on the supply of intracutaneous reaction test materials from pharmaceutical companies. In: Japanese Journal of Chemotherapy. 2013 ; Vol. 61, No. 3. pp. 297-300.
@article{4a4844e6fbc24ba892ace05bc21c6f03,
title = "A questionnaire survey on the supply of intracutaneous reaction test materials from pharmaceutical companies",
abstract = "Since the intracutaneous reaction tests of injectable antimicrobials were concluded to be ineffective in the prediction of anaphylactic reaction due to these drugs in 2003, it was decided to suspend these reaction tests. However, the materials for intracutaneous reaction tests remain available. We conducted a questionnaire involving 38 pharmaceutical companies that produce intracutaneous reaction test materials. We collected valid responses from 32 companies (a response rate of 91{\%}). In 2009, intracutaneous reaction test materials were available for 93 drug products, although the number of shipments had decreased to 1,630,000. As the reason for continued supply of intracutaneous reaction test materials to clinical facilities, 28 of the 29 companies that responded to the question cited {"}request from clinical facilities{"}. The pharmaceutical companies received inquiries regarding the methods for predicting anaphylaxis caused by antimicrobials, including the preparation of test solutions, the method for conducting a prick test, and information provided by relevant academic societies and the Ministry of Health, Labour and Welfare. To avoid intracutaneous reaction tests to predict anaphylaxis, and provide effective antimicrobial therapy in clinical practice, it is important for medical professionals including MR and MS as well as medical doctors and pharmacists, to share proper information regarding the method to predict anaphylaxis due to injectable antimicrobials.",
keywords = "Drug allergy, Intracutaneous reaction test, Questionnaire survey",
author = "Seiji Hori and Yoshihiro Yamakawa and Kayoko Maezawa and Tomoko Terajima and Masaki Yoshida and Junko Kizu",
year = "2013",
month = "5",
language = "English",
volume = "61",
pages = "297--300",
journal = "Japanese Journal of Chemotherapy",
issn = "1340-7007",
publisher = "Japan Society of Chemotherapy",
number = "3",

}

TY - JOUR

T1 - A questionnaire survey on the supply of intracutaneous reaction test materials from pharmaceutical companies

AU - Hori, Seiji

AU - Yamakawa, Yoshihiro

AU - Maezawa, Kayoko

AU - Terajima, Tomoko

AU - Yoshida, Masaki

AU - Kizu, Junko

PY - 2013/5

Y1 - 2013/5

N2 - Since the intracutaneous reaction tests of injectable antimicrobials were concluded to be ineffective in the prediction of anaphylactic reaction due to these drugs in 2003, it was decided to suspend these reaction tests. However, the materials for intracutaneous reaction tests remain available. We conducted a questionnaire involving 38 pharmaceutical companies that produce intracutaneous reaction test materials. We collected valid responses from 32 companies (a response rate of 91%). In 2009, intracutaneous reaction test materials were available for 93 drug products, although the number of shipments had decreased to 1,630,000. As the reason for continued supply of intracutaneous reaction test materials to clinical facilities, 28 of the 29 companies that responded to the question cited "request from clinical facilities". The pharmaceutical companies received inquiries regarding the methods for predicting anaphylaxis caused by antimicrobials, including the preparation of test solutions, the method for conducting a prick test, and information provided by relevant academic societies and the Ministry of Health, Labour and Welfare. To avoid intracutaneous reaction tests to predict anaphylaxis, and provide effective antimicrobial therapy in clinical practice, it is important for medical professionals including MR and MS as well as medical doctors and pharmacists, to share proper information regarding the method to predict anaphylaxis due to injectable antimicrobials.

AB - Since the intracutaneous reaction tests of injectable antimicrobials were concluded to be ineffective in the prediction of anaphylactic reaction due to these drugs in 2003, it was decided to suspend these reaction tests. However, the materials for intracutaneous reaction tests remain available. We conducted a questionnaire involving 38 pharmaceutical companies that produce intracutaneous reaction test materials. We collected valid responses from 32 companies (a response rate of 91%). In 2009, intracutaneous reaction test materials were available for 93 drug products, although the number of shipments had decreased to 1,630,000. As the reason for continued supply of intracutaneous reaction test materials to clinical facilities, 28 of the 29 companies that responded to the question cited "request from clinical facilities". The pharmaceutical companies received inquiries regarding the methods for predicting anaphylaxis caused by antimicrobials, including the preparation of test solutions, the method for conducting a prick test, and information provided by relevant academic societies and the Ministry of Health, Labour and Welfare. To avoid intracutaneous reaction tests to predict anaphylaxis, and provide effective antimicrobial therapy in clinical practice, it is important for medical professionals including MR and MS as well as medical doctors and pharmacists, to share proper information regarding the method to predict anaphylaxis due to injectable antimicrobials.

KW - Drug allergy

KW - Intracutaneous reaction test

KW - Questionnaire survey

UR - http://www.scopus.com/inward/record.url?scp=84878394908&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84878394908&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84878394908

VL - 61

SP - 297

EP - 300

JO - Japanese Journal of Chemotherapy

JF - Japanese Journal of Chemotherapy

SN - 1340-7007

IS - 3

ER -