A radiation hybrid map of mouse genes

Thomas J. Hudson, Deanna M. Church, Simon Greenaway, Huy Nguyen, April Cook, Robert G. Steen, William J. Van Etten, Andrew B. Castle, Mark A. Strivens, Pamela Trickett, Christine Heuston, Claire Davison, Anne Southwell, Rachel Hardisty, Anabel Varela-Carver, Andrew R. Haynes, Patricia Rodriguez-Tome, Hirofumi Doi, Minoru Ko, Joan PontiusLynn Schriml, Lukas Wagner, Donna Maglott, Steve D M Brown, Eric S. Lander, Greg Schuler, Paul Denny

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

A comprehensive gene-based map of a genome is a powerful tool for genetic studies and is especially useful for the positional cloning and positional candidate approaches. The availability of gene maps for multiple organisms provides the foundation for detailed conserved-orthology maps showing the correspondence between conserved genomic segments. These maps make it possible to use cross-species information in gene hunts and shed light on the evolutionary forces that shape the genome. Here we report a radiation hybrid map of mouse genes, a combined project of the Whitehead Institute/Massachusetts Institute of Technology Center for Genome Research, the Medical Research Council UK Mouse Genome Centre, and the National Center for Biotechnology Information. The map contains 11,109 genes, screened against the T31 RH panel and positioned relative to a reference map containing 2,280 mouse genetic markers. It includes 3,658 genes homologous to the human genome sequence and provides a framework for overlaying the human genome sequence to the mouse and for sequencing the mouse genome.

Original languageEnglish
Pages (from-to)201-205
Number of pages5
JournalNature Genetics
Volume29
Issue number2
DOIs
Publication statusPublished - 2001
Externally publishedYes

Fingerprint

Radiation Hybrid Mapping
Genome
Genes
Human Genome
Information Centers
Biotechnology
Genetic Markers
Biomedical Research
Organism Cloning
Technology
Research

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

Cite this

Hudson, T. J., Church, D. M., Greenaway, S., Nguyen, H., Cook, A., Steen, R. G., ... Denny, P. (2001). A radiation hybrid map of mouse genes. Nature Genetics, 29(2), 201-205. https://doi.org/10.1038/ng1001-201

A radiation hybrid map of mouse genes. / Hudson, Thomas J.; Church, Deanna M.; Greenaway, Simon; Nguyen, Huy; Cook, April; Steen, Robert G.; Van Etten, William J.; Castle, Andrew B.; Strivens, Mark A.; Trickett, Pamela; Heuston, Christine; Davison, Claire; Southwell, Anne; Hardisty, Rachel; Varela-Carver, Anabel; Haynes, Andrew R.; Rodriguez-Tome, Patricia; Doi, Hirofumi; Ko, Minoru; Pontius, Joan; Schriml, Lynn; Wagner, Lukas; Maglott, Donna; Brown, Steve D M; Lander, Eric S.; Schuler, Greg; Denny, Paul.

In: Nature Genetics, Vol. 29, No. 2, 2001, p. 201-205.

Research output: Contribution to journalArticle

Hudson, TJ, Church, DM, Greenaway, S, Nguyen, H, Cook, A, Steen, RG, Van Etten, WJ, Castle, AB, Strivens, MA, Trickett, P, Heuston, C, Davison, C, Southwell, A, Hardisty, R, Varela-Carver, A, Haynes, AR, Rodriguez-Tome, P, Doi, H, Ko, M, Pontius, J, Schriml, L, Wagner, L, Maglott, D, Brown, SDM, Lander, ES, Schuler, G & Denny, P 2001, 'A radiation hybrid map of mouse genes', Nature Genetics, vol. 29, no. 2, pp. 201-205. https://doi.org/10.1038/ng1001-201
Hudson TJ, Church DM, Greenaway S, Nguyen H, Cook A, Steen RG et al. A radiation hybrid map of mouse genes. Nature Genetics. 2001;29(2):201-205. https://doi.org/10.1038/ng1001-201
Hudson, Thomas J. ; Church, Deanna M. ; Greenaway, Simon ; Nguyen, Huy ; Cook, April ; Steen, Robert G. ; Van Etten, William J. ; Castle, Andrew B. ; Strivens, Mark A. ; Trickett, Pamela ; Heuston, Christine ; Davison, Claire ; Southwell, Anne ; Hardisty, Rachel ; Varela-Carver, Anabel ; Haynes, Andrew R. ; Rodriguez-Tome, Patricia ; Doi, Hirofumi ; Ko, Minoru ; Pontius, Joan ; Schriml, Lynn ; Wagner, Lukas ; Maglott, Donna ; Brown, Steve D M ; Lander, Eric S. ; Schuler, Greg ; Denny, Paul. / A radiation hybrid map of mouse genes. In: Nature Genetics. 2001 ; Vol. 29, No. 2. pp. 201-205.
@article{4a38077ffe094fc9904776f802370c28,
title = "A radiation hybrid map of mouse genes",
abstract = "A comprehensive gene-based map of a genome is a powerful tool for genetic studies and is especially useful for the positional cloning and positional candidate approaches. The availability of gene maps for multiple organisms provides the foundation for detailed conserved-orthology maps showing the correspondence between conserved genomic segments. These maps make it possible to use cross-species information in gene hunts and shed light on the evolutionary forces that shape the genome. Here we report a radiation hybrid map of mouse genes, a combined project of the Whitehead Institute/Massachusetts Institute of Technology Center for Genome Research, the Medical Research Council UK Mouse Genome Centre, and the National Center for Biotechnology Information. The map contains 11,109 genes, screened against the T31 RH panel and positioned relative to a reference map containing 2,280 mouse genetic markers. It includes 3,658 genes homologous to the human genome sequence and provides a framework for overlaying the human genome sequence to the mouse and for sequencing the mouse genome.",
author = "Hudson, {Thomas J.} and Church, {Deanna M.} and Simon Greenaway and Huy Nguyen and April Cook and Steen, {Robert G.} and {Van Etten}, {William J.} and Castle, {Andrew B.} and Strivens, {Mark A.} and Pamela Trickett and Christine Heuston and Claire Davison and Anne Southwell and Rachel Hardisty and Anabel Varela-Carver and Haynes, {Andrew R.} and Patricia Rodriguez-Tome and Hirofumi Doi and Minoru Ko and Joan Pontius and Lynn Schriml and Lukas Wagner and Donna Maglott and Brown, {Steve D M} and Lander, {Eric S.} and Greg Schuler and Paul Denny",
year = "2001",
doi = "10.1038/ng1001-201",
language = "English",
volume = "29",
pages = "201--205",
journal = "Nature Genetics",
issn = "1061-4036",
publisher = "Nature Publishing Group",
number = "2",

}

TY - JOUR

T1 - A radiation hybrid map of mouse genes

AU - Hudson, Thomas J.

AU - Church, Deanna M.

AU - Greenaway, Simon

AU - Nguyen, Huy

AU - Cook, April

AU - Steen, Robert G.

AU - Van Etten, William J.

AU - Castle, Andrew B.

AU - Strivens, Mark A.

AU - Trickett, Pamela

AU - Heuston, Christine

AU - Davison, Claire

AU - Southwell, Anne

AU - Hardisty, Rachel

AU - Varela-Carver, Anabel

AU - Haynes, Andrew R.

AU - Rodriguez-Tome, Patricia

AU - Doi, Hirofumi

AU - Ko, Minoru

AU - Pontius, Joan

AU - Schriml, Lynn

AU - Wagner, Lukas

AU - Maglott, Donna

AU - Brown, Steve D M

AU - Lander, Eric S.

AU - Schuler, Greg

AU - Denny, Paul

PY - 2001

Y1 - 2001

N2 - A comprehensive gene-based map of a genome is a powerful tool for genetic studies and is especially useful for the positional cloning and positional candidate approaches. The availability of gene maps for multiple organisms provides the foundation for detailed conserved-orthology maps showing the correspondence between conserved genomic segments. These maps make it possible to use cross-species information in gene hunts and shed light on the evolutionary forces that shape the genome. Here we report a radiation hybrid map of mouse genes, a combined project of the Whitehead Institute/Massachusetts Institute of Technology Center for Genome Research, the Medical Research Council UK Mouse Genome Centre, and the National Center for Biotechnology Information. The map contains 11,109 genes, screened against the T31 RH panel and positioned relative to a reference map containing 2,280 mouse genetic markers. It includes 3,658 genes homologous to the human genome sequence and provides a framework for overlaying the human genome sequence to the mouse and for sequencing the mouse genome.

AB - A comprehensive gene-based map of a genome is a powerful tool for genetic studies and is especially useful for the positional cloning and positional candidate approaches. The availability of gene maps for multiple organisms provides the foundation for detailed conserved-orthology maps showing the correspondence between conserved genomic segments. These maps make it possible to use cross-species information in gene hunts and shed light on the evolutionary forces that shape the genome. Here we report a radiation hybrid map of mouse genes, a combined project of the Whitehead Institute/Massachusetts Institute of Technology Center for Genome Research, the Medical Research Council UK Mouse Genome Centre, and the National Center for Biotechnology Information. The map contains 11,109 genes, screened against the T31 RH panel and positioned relative to a reference map containing 2,280 mouse genetic markers. It includes 3,658 genes homologous to the human genome sequence and provides a framework for overlaying the human genome sequence to the mouse and for sequencing the mouse genome.

UR - http://www.scopus.com/inward/record.url?scp=0034785351&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034785351&partnerID=8YFLogxK

U2 - 10.1038/ng1001-201

DO - 10.1038/ng1001-201

M3 - Article

C2 - 11586302

AN - SCOPUS:0034785351

VL - 29

SP - 201

EP - 205

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 2

ER -