A randomized Phase III trial of thoracoscopic versus open esophagectomy for thoracic esophageal cancer: Japan Clinical Oncology Group Study JCOG1409

Japan Esophageal Oncology Group/Japan Clinical Oncology Group, Hiroya Takeuchi

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

A randomized Phase III study was commenced in May 2015 to confirm the non-inferiority of thoracoscopic esophagectomy to open esophagectomy in terms of overall survival for clinical Stage I-III esophageal cancer. A total of 300 patients will be accrued from Japanese institutions over 6 years. The primary endpoint is overall survival. The secondary endpoints are relapse-free survival, proportion of patients with R0 resection, proportion of patients who underwent re-operation, adverse events, postoperative respiratory function change, postoperative quality-of-life score (EORTC QLQC30), and proportion of patients who need conversion from thoracoscopic surgery to open surgery. This trial has been registered in the UMIN Clinical Trials Registry as UMIN000017628.

Original languageEnglish
Article numberhyv178
Pages (from-to)174-177
Number of pages4
JournalJapanese Journal of Clinical Oncology
Volume46
Issue number2
DOIs
Publication statusPublished - 2016 Feb 1

Keywords

  • Open esophagectomy
  • Phase III
  • Thoracoscopic esophagectomy

ASJC Scopus subject areas

  • Oncology
  • Cancer Research
  • Radiology Nuclear Medicine and imaging

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