A Reticuloendothelial System-Activating Arabinoxylan from the Bark of Cinnamomum cassia

Mieko Kanari; Masashi Tomoda; Ryoko Gonda; Noriko Shimizu; Miyako Kimura; K. Kawabe; Masami Kawaguchi

doi:10.1248/cpb.37.3191

A Reticuloendothelial System-Activating Arabinoxylan from the Bark of Cinnamomum cassia

Mieko Kanari, Masashi Tomoda, Ryoko Gonda, Noriko Shimizu, Miyako Kimura, K. Kawabe, Masami Kawaguchi

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

A neutral polysaccharide, named cinnaman AX, was isolated from the dried bark of Cinnamomum cassia blume. It was homogeneous on electrophoresis and gel chromatography. It is composed of L-arabinose D-xylose in the molar ratio of 4:3, and its molecular weight was estimated to be about 1.0 x 106. Methylation analysis, carbon-13 nuclear magnetic resonance and controlled Smith degradation studies enabled elucidation of its structural features. It showed remarkable reticuloendothelial system-potentiating activity in a carbon clearance test.

Original language	English
Pages (from-to)	3191-3194
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	37
Issue number	12
DOIs	https://doi.org/10.1248/cpb.37.3191
Publication status	Published - 1989

Keywords

Cinnamomi Cortex
Cinnamomum cassia
Smith degradation
arabinoxylan
bark
cinnaman AX
immunological activity
methylation analysis
polysaccharide structure
reticuloendothelial system

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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10.1248/cpb.37.3191

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abstract = "A neutral polysaccharide, named cinnaman AX, was isolated from the dried bark of Cinnamomum cassia blume. It was homogeneous on electrophoresis and gel chromatography. It is composed of L-arabinose D-xylose in the molar ratio of 4:3, and its molecular weight was estimated to be about 1.0 x 106. Methylation analysis, carbon-13 nuclear magnetic resonance and controlled Smith degradation studies enabled elucidation of its structural features. It showed remarkable reticuloendothelial system-potentiating activity in a carbon clearance test.",

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AU - Kanari, Mieko

AU - Tomoda, Masashi

AU - Gonda, Ryoko

AU - Shimizu, Noriko

AU - Kimura, Miyako

AU - Kawabe, K.

AU - Kawaguchi, Masami

PY - 1989

Y1 - 1989

N2 - A neutral polysaccharide, named cinnaman AX, was isolated from the dried bark of Cinnamomum cassia blume. It was homogeneous on electrophoresis and gel chromatography. It is composed of L-arabinose D-xylose in the molar ratio of 4:3, and its molecular weight was estimated to be about 1.0 x 106. Methylation analysis, carbon-13 nuclear magnetic resonance and controlled Smith degradation studies enabled elucidation of its structural features. It showed remarkable reticuloendothelial system-potentiating activity in a carbon clearance test.

AB - A neutral polysaccharide, named cinnaman AX, was isolated from the dried bark of Cinnamomum cassia blume. It was homogeneous on electrophoresis and gel chromatography. It is composed of L-arabinose D-xylose in the molar ratio of 4:3, and its molecular weight was estimated to be about 1.0 x 106. Methylation analysis, carbon-13 nuclear magnetic resonance and controlled Smith degradation studies enabled elucidation of its structural features. It showed remarkable reticuloendothelial system-potentiating activity in a carbon clearance test.

KW - Cinnamomi Cortex

KW - Cinnamomum cassia

KW - Smith degradation

KW - arabinoxylan

KW - bark

KW - cinnaman AX

KW - immunological activity

KW - methylation analysis

KW - polysaccharide structure

KW - reticuloendothelial system

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A Reticuloendothelial System-Activating Arabinoxylan from the Bark of Cinnamomum cassia

Abstract

Keywords

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