A reticuloendothelial system-activating glycan from the barks ofEucommia ulmoides

Masashi Tomoda; Ryo ̃ko Gonda; Noriko Shimizu; Mieko Kanari

doi:10.1016/0031-9422(90)80163-B

A reticuloendothelial system-activating glycan from the barks ofEucommia ulmoides

Masashi Tomoda, Ryo ̃ko Gonda, Noriko Shimizu, Mieko Kanari

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

From the hot water extract of the barks ofEucommia ulmoides, a glycan, named eucomman B, has been isolated by treatment with cetyltrimethylammonium bromide followed by fractionation on DEAE-Sephadex A-25 and chromatography on Sephacryl S-300 columns. Chemical and spectroscopic studies established that the glycan possesses mainly α-1,2-linkedl-rhamno-α-1,4-linkedd-galacturonan structure. α-1,5-Linkedl-arabinofuranose, α-1,3-linkedl-arabinopyranose, β-1,3- and β-1,4-linkedd-galactose, 2,4-branchedl-rhamnose and 3,4-branchedd-galacturonic acid residues were also identified as the component sugar units. The glycan showed significant reticuloendothelial system potentiating activity in the carbon clearance test.

Original language	English
Pages (from-to)	3091-3094
Number of pages	4
Journal	Phytochemistry
Volume	29
Issue number	10
DOIs	https://doi.org/10.1016/0031-9422(90)80163-B
Publication status	Published - 1990

Keywords

Eucommia ulmoides
Eucommiaceae
bark
phagocytic activity.
polysaccharide
structural analysis

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Plant Science
Horticulture

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10.1016/0031-9422(90)80163-B

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@article{22110615be184622982553bc058eb73a,

title = "A reticuloendothelial system-activating glycan from the barks ofEucommia ulmoides",

abstract = "From the hot water extract of the barks ofEucommia ulmoides, a glycan, named eucomman B, has been isolated by treatment with cetyltrimethylammonium bromide followed by fractionation on DEAE-Sephadex A-25 and chromatography on Sephacryl S-300 columns. Chemical and spectroscopic studies established that the glycan possesses mainly α-1,2-linkedl-rhamno-α-1,4-linkedd-galacturonan structure. α-1,5-Linkedl-arabinofuranose, α-1,3-linkedl-arabinopyranose, β-1,3- and β-1,4-linkedd-galactose, 2,4-branchedl-rhamnose and 3,4-branchedd-galacturonic acid residues were also identified as the component sugar units. The glycan showed significant reticuloendothelial system potentiating activity in the carbon clearance test.",

keywords = "Eucommia ulmoides, Eucommiaceae, bark, phagocytic activity., polysaccharide, structural analysis",

author = "Masashi Tomoda and Gonda, {Ryo{\~ }ko} and Noriko Shimizu and Mieko Kanari",

note = "Funding Information: Acknowledgement-This work was supported m part by The Science Research PromotIon Fund of the Japan Private School PromotIon Foundation.",

year = "1990",

doi = "10.1016/0031-9422(90)80163-B",

language = "English",

volume = "29",

pages = "3091--3094",

journal = "Phytochemistry",

issn = "0031-9422",

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T1 - A reticuloendothelial system-activating glycan from the barks ofEucommia ulmoides

AU - Tomoda, Masashi

AU - Gonda, Ryo ̃ko

AU - Shimizu, Noriko

AU - Kanari, Mieko

N1 - Funding Information: Acknowledgement-This work was supported m part by The Science Research PromotIon Fund of the Japan Private School PromotIon Foundation.

PY - 1990

Y1 - 1990

N2 - From the hot water extract of the barks ofEucommia ulmoides, a glycan, named eucomman B, has been isolated by treatment with cetyltrimethylammonium bromide followed by fractionation on DEAE-Sephadex A-25 and chromatography on Sephacryl S-300 columns. Chemical and spectroscopic studies established that the glycan possesses mainly α-1,2-linkedl-rhamno-α-1,4-linkedd-galacturonan structure. α-1,5-Linkedl-arabinofuranose, α-1,3-linkedl-arabinopyranose, β-1,3- and β-1,4-linkedd-galactose, 2,4-branchedl-rhamnose and 3,4-branchedd-galacturonic acid residues were also identified as the component sugar units. The glycan showed significant reticuloendothelial system potentiating activity in the carbon clearance test.

AB - From the hot water extract of the barks ofEucommia ulmoides, a glycan, named eucomman B, has been isolated by treatment with cetyltrimethylammonium bromide followed by fractionation on DEAE-Sephadex A-25 and chromatography on Sephacryl S-300 columns. Chemical and spectroscopic studies established that the glycan possesses mainly α-1,2-linkedl-rhamno-α-1,4-linkedd-galacturonan structure. α-1,5-Linkedl-arabinofuranose, α-1,3-linkedl-arabinopyranose, β-1,3- and β-1,4-linkedd-galactose, 2,4-branchedl-rhamnose and 3,4-branchedd-galacturonic acid residues were also identified as the component sugar units. The glycan showed significant reticuloendothelial system potentiating activity in the carbon clearance test.

KW - Eucommia ulmoides

KW - Eucommiaceae

KW - bark

KW - phagocytic activity.

KW - polysaccharide

KW - structural analysis

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U2 - 10.1016/0031-9422(90)80163-B

DO - 10.1016/0031-9422(90)80163-B

M3 - Article

AN - SCOPUS:0343672858

SN - 0031-9422

VL - 29

SP - 3091

EP - 3094

JO - Phytochemistry

JF - Phytochemistry

IS - 10

ER -

A reticuloendothelial system-activating glycan from the barks ofEucommia ulmoides

Abstract

Keywords

ASJC Scopus subject areas

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