A reticuloendothelial system-activating glycan from the barks ofEucommia ulmoides

Masashi Tomoda, Ryo ̃ko Gonda, Noriko Shimizu, Mieko Kanari

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

From the hot water extract of the barks ofEucommia ulmoides, a glycan, named eucomman B, has been isolated by treatment with cetyltrimethylammonium bromide followed by fractionation on DEAE-Sephadex A-25 and chromatography on Sephacryl S-300 columns. Chemical and spectroscopic studies established that the glycan possesses mainly α-1,2-linkedl-rhamno-α-1,4-linkedd-galacturonan structure. α-1,5-Linkedl-arabinofuranose, α-1,3-linkedl-arabinopyranose, β-1,3- and β-1,4-linkedd-galactose, 2,4-branchedl-rhamnose and 3,4-branchedd-galacturonic acid residues were also identified as the component sugar units. The glycan showed significant reticuloendothelial system potentiating activity in the carbon clearance test.

Original languageEnglish
Pages (from-to)3091-3094
Number of pages4
JournalPhytochemistry
Volume29
Issue number10
DOIs
Publication statusPublished - 1990
Externally publishedYes

Fingerprint

reticuloendothelial system
Mononuclear Phagocyte System
Polysaccharides
bark
polysaccharides
Rhamnose
galacturonic acid
rhamnose
Fractionation
Chromatography
Galactose
Sugars
galactose
fractionation
chromatography
Carbon
sugars
Water
carbon
extracts

Keywords

  • bark
  • Eucommia ulmoides
  • Eucommiaceae
  • phagocytic activity.
  • polysaccharide
  • structural analysis

ASJC Scopus subject areas

  • Plant Science
  • Biochemistry
  • Molecular Biology
  • Organic Chemistry
  • Drug Discovery

Cite this

A reticuloendothelial system-activating glycan from the barks ofEucommia ulmoides. / Tomoda, Masashi; Gonda, Ryo ̃ko; Shimizu, Noriko; Kanari, Mieko.

In: Phytochemistry, Vol. 29, No. 10, 1990, p. 3091-3094.

Research output: Contribution to journalArticle

Tomoda, Masashi ; Gonda, Ryo ̃ko ; Shimizu, Noriko ; Kanari, Mieko. / A reticuloendothelial system-activating glycan from the barks ofEucommia ulmoides. In: Phytochemistry. 1990 ; Vol. 29, No. 10. pp. 3091-3094.
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