A reticuloendothelial system activating glycan from the rhizomes of Curcuma longa

Masashi Tomoda, Ryoko Gonda, Noriko Shimizu, Mieko Kanari, Miyako Kimura

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

From the hot water extract of the rhizomes of Curcuma longa, a glycan, named ukonan A, has been isolated by fractionation on DEAE-Sephadex A-25 followed by chromatography on Con A-Sepharose and Sephacryl S-300 columns. Chemical and spectroscopic studies established that the glycan possesses an α-l-arabino-3,6-β-d-galactan structure. α-1,3-Linked l-arabinopyranose, β-3,4-branched d-xylose, α-1,4-linked d-glucose, α-2,4-branched l-rhamnose and α-1,4-linked d-galacturonic acid residues were also identified as the component sugar units. The glycan showed remarkable reticuloendothelial system potentiating activity in the carbon clearance test.

Original languageEnglish
Pages (from-to)1083-1086
Number of pages4
JournalPhytochemistry
Volume29
Issue number4
DOIs
Publication statusPublished - 1990
Externally publishedYes

Fingerprint

reticuloendothelial system
Curcuma
Curcuma longa
Mononuclear Phagocyte System
Rhizome
rhizomes
Polysaccharides
polysaccharides
Galactans
galactans
Rhamnose
galacturonic acid
rhamnose
Xylose
Fractionation
Chromatography
xylose
Sugars
agarose
fractionation

Keywords

  • Curcuma longa
  • phagocytic activity
  • polysaccharide
  • rhizome
  • structural analysis.
  • Zingiberaceae

ASJC Scopus subject areas

  • Plant Science
  • Biochemistry
  • Molecular Biology
  • Organic Chemistry
  • Drug Discovery

Cite this

A reticuloendothelial system activating glycan from the rhizomes of Curcuma longa. / Tomoda, Masashi; Gonda, Ryoko; Shimizu, Noriko; Kanari, Mieko; Kimura, Miyako.

In: Phytochemistry, Vol. 29, No. 4, 1990, p. 1083-1086.

Research output: Contribution to journalArticle

Tomoda, Masashi ; Gonda, Ryoko ; Shimizu, Noriko ; Kanari, Mieko ; Kimura, Miyako. / A reticuloendothelial system activating glycan from the rhizomes of Curcuma longa. In: Phytochemistry. 1990 ; Vol. 29, No. 4. pp. 1083-1086.
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