Abstract
The effect of water-miscible organic solvents on the stability of filamentous phages displaying a random peptide library was investigated. A kinetic analysis of the time course of viral infectivity indicated that the transition between the noninfectious and infectious form was directly related to the concentration of organic solvent.
Original language | English |
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Pages (from-to) | 269-271 |
Number of pages | 3 |
Journal | Biomolecular Engineering |
Volume | 24 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2007 Jun 1 |
Keywords
- 50% inhibitory dose
- Non-aqueous media
- Organic solvent
- Peptide library
- Phage display
- Viral infectivity
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Molecular Biology