A simple two-transition model for loss of infectivity of phages on exposure to organic solvent

Teruhiko Matsubara; Wakako Emoto; Katsuhiro Kawashiro

doi:10.1016/j.bioeng.2007.02.002

A simple two-transition model for loss of infectivity of phages on exposure to organic solvent

Teruhiko Matsubara, Wakako Emoto, Katsuhiro Kawashiro

Department of Biosciences and Informatics

Research output: Contribution to journal › Article

5 Citations (Scopus)

Abstract

The effect of water-miscible organic solvents on the stability of filamentous phages displaying a random peptide library was investigated. A kinetic analysis of the time course of viral infectivity indicated that the transition between the noninfectious and infectious form was directly related to the concentration of organic solvent.

Original language	English
Pages (from-to)	269-271
Number of pages	3
Journal	Biomolecular Engineering
Volume	24
Issue number	2
DOIs	https://doi.org/10.1016/j.bioeng.2007.02.002
Publication status	Published - 2007 Jun 1

Fingerprint

Keywords

50% inhibitory dose
Non-aqueous media
Organic solvent
Peptide library
Phage display
Viral infectivity

ASJC Scopus subject areas

Biotechnology
Bioengineering
Molecular Biology

Cite this

Matsubara, T., Emoto, W., & Kawashiro, K. (2007). A simple two-transition model for loss of infectivity of phages on exposure to organic solvent. Biomolecular Engineering, 24(2), 269-271. https://doi.org/10.1016/j.bioeng.2007.02.002

@article{77fbd88671424924963b3e99f1a43566,

title = "A simple two-transition model for loss of infectivity of phages on exposure to organic solvent",

abstract = "The effect of water-miscible organic solvents on the stability of filamentous phages displaying a random peptide library was investigated. A kinetic analysis of the time course of viral infectivity indicated that the transition between the noninfectious and infectious form was directly related to the concentration of organic solvent.",

keywords = "50% inhibitory dose, Non-aqueous media, Organic solvent, Peptide library, Phage display, Viral infectivity",

author = "Teruhiko Matsubara and Wakako Emoto and Katsuhiro Kawashiro",

year = "2007",

month = jun,

day = "1",

doi = "10.1016/j.bioeng.2007.02.002",

language = "English",

volume = "24",

pages = "269--271",

journal = "New Biotechnology",

issn = "1871-6784",

publisher = "Elsevier",

number = "2",

}

TY - JOUR

T1 - A simple two-transition model for loss of infectivity of phages on exposure to organic solvent

AU - Matsubara, Teruhiko

AU - Emoto, Wakako

AU - Kawashiro, Katsuhiro

PY - 2007/6/1

Y1 - 2007/6/1

N2 - The effect of water-miscible organic solvents on the stability of filamentous phages displaying a random peptide library was investigated. A kinetic analysis of the time course of viral infectivity indicated that the transition between the noninfectious and infectious form was directly related to the concentration of organic solvent.

AB - The effect of water-miscible organic solvents on the stability of filamentous phages displaying a random peptide library was investigated. A kinetic analysis of the time course of viral infectivity indicated that the transition between the noninfectious and infectious form was directly related to the concentration of organic solvent.

KW - 50% inhibitory dose

KW - Non-aqueous media

KW - Organic solvent

KW - Peptide library

KW - Phage display

KW - Viral infectivity

UR - http://www.scopus.com/inward/record.url?scp=34248551675&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34248551675&partnerID=8YFLogxK

U2 - 10.1016/j.bioeng.2007.02.002

DO - 10.1016/j.bioeng.2007.02.002

M3 - Article

C2 - 17353146

AN - SCOPUS:34248551675

VL - 24

SP - 269

EP - 271

JO - New Biotechnology

JF - New Biotechnology

SN - 1871-6784

IS - 2

ER -

Access to Document

10.1016/j.bioeng.2007.02.002