(-)-Dihydroedulan II and related compounds were synthesized from (2R,1′RS)-dihydro-α-ionol, which was prepared by lipase-catalyzed enantioselective transesterification of the corresponding diastereomeric mixture as the key-step. Fungal allylic oxidation of (-)-dihydroedulan II worked well to afford a corresponding alcohol as well as (+)-dihydroedulan-8-one.
|Number of pages||10|
|Publication status||Published - 1991 Aug 26|
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry