AbeM, an H+-coupled Acinetobacter baumannii multidrug efflux pump belonging to the MATE family of transporters

Xian Zhong Su, Jing Chen, Tohru Mizushima, Teruo Kuroda, Tomofusa Tsuchiya

Research output: Contribution to journalArticle

126 Citations (Scopus)

Abstract

We cloned a gene, abeM, for a multidrug efflux pump from Acinetobacter baumannii using Escherichia coli as the host. Sequence analysis revealed that AbeM is a member of the MATE family of pumps. AbeM was found to be an H +-coupled multidrug efflux pump and a unique member of the MATE family.

Original languageEnglish
Pages (from-to)4362-4364
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume49
Issue number10
DOIs
Publication statusPublished - 2005 Oct

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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