Ablation characteristics of myocardium tissue in the UV spectral region: Porcine myocardium tissue study in vitro

T. Shimada, S. Sato, M. Ishihara, T. Arai, T. Matsui, A. Kurita, M. Kikuchi, H. Wakisaka, H. Ashida, M. Obara

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

TMLR (Transmyocardial Laser Revascularization) has been introduced to treat severe coronary artery disease that cannot be treated by conventional treatments such as PTCA (percutaneous transluminal coronary angioplasty) or CABG (coronary artery bypass grafting). TMLR is a laser-ablation-based surgical procedure in which laser channels are created through the myocardium to increase the flow of blood in the oxygen-starved tissue, thereby relieving angina and debilitating symptons of coronary artery disease. For this treatment, a high-power 10.6-μm CO2 laser has been mainly used to create the channels. Recently, however, a variety of lasers including 2.1-μm Ho:YAG and 308-nm XeCl excimer lasers have appeared to be applied. Although many clinical results are reported, no comprehensive study has been, so far, performed to reveal the optimum laser irradiation conditions for this treatment. The authors investigated the dependence of the irradiation wavelength on the ablation characteristics of the myocardial tissue in the UV (ultraviolet) spectral region, where damage-free ablation was expected. As a light source for ablation, the authors used a tunable OPO (optical parametric oscillator).

Original languageEnglish
Title of host publicationCLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1231-1232
Number of pages2
ISBN (Electronic)0780356616, 9780780356610
DOIs
Publication statusPublished - 1999 Jan 1
Event1999 Pacific Rim Conference on Lasers and Electro-Optics, CLEO/Pacific Rim 1999 - Seoul, Korea, Republic of
Duration: 1999 Aug 301999 Sep 3

Publication series

NameCLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics
Volume4

Conference

Conference1999 Pacific Rim Conference on Lasers and Electro-Optics, CLEO/Pacific Rim 1999
CountryKorea, Republic of
CitySeoul
Period99/8/3099/9/3

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Computer Networks and Communications
  • Physics and Astronomy(all)

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    Shimada, T., Sato, S., Ishihara, M., Arai, T., Matsui, T., Kurita, A., Kikuchi, M., Wakisaka, H., Ashida, H., & Obara, M. (1999). Ablation characteristics of myocardium tissue in the UV spectral region: Porcine myocardium tissue study in vitro. In CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics (pp. 1231-1232). [814750] (CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics; Vol. 4). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CLEOPR.1999.814750