Abnormal first-trimester fetal nuchal translucency and amniotic band syndrome

Takayuki Higuchi, Mamoru Tanaka, Keiko Kuroda, Akira Yabuno, Seon Hye Kim, Satoshi Asai, Sokichi Iwata, Kei Miyakoshi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We report a case of amniotic band syndrome diagnosed prenatally by serial sonographic examinations. Our initial sonographic image showed a large fetal nuchal translucency (NT) at 12 weeks' gestation. Repeated fetal ultrasound images revealed an amniotic band and right upper limb anomaly. Fetal MRI at 19 weeks' gestation revealed right forearm hypoplasia and pseudosyndactyly. The fetus was prenatally diagnosed with amniotic band syndrome and was suspected of having severe functional impairment of the deformed limb. The parents decided to terminate the pregnancy at 21 weeks' gestation. In fetuses with aneuploidy and various structural and genetic abnormalities, the NT thickness is increased in the first trimester. As far as we are aware, this is the first case report of increased NT and limb anomaly associated with amniotic band syndrome. In chromosomally normal fetuses with increased NT, intensive sonographic follow-up should provide grounds for a precise antenatal diagnosis.

Original languageEnglish
Pages (from-to)177-180
Number of pages4
JournalJournal of Medical Ultrasonics
Volume39
Issue number3
DOIs
Publication statusPublished - 2012 Jul

Fingerprint

Amniotic Band Syndrome
Nuchal Translucency Measurement
First Pregnancy Trimester
Pregnancy
Fetus
Extremities
Aneuploidy
Prenatal Diagnosis
Forearm
Upper Extremity

Keywords

  • Amniotic band syndrome
  • Nuchal translucency

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Abnormal first-trimester fetal nuchal translucency and amniotic band syndrome. / Higuchi, Takayuki; Tanaka, Mamoru; Kuroda, Keiko; Yabuno, Akira; Kim, Seon Hye; Asai, Satoshi; Iwata, Sokichi; Miyakoshi, Kei.

In: Journal of Medical Ultrasonics, Vol. 39, No. 3, 07.2012, p. 177-180.

Research output: Contribution to journalArticle

Higuchi, Takayuki ; Tanaka, Mamoru ; Kuroda, Keiko ; Yabuno, Akira ; Kim, Seon Hye ; Asai, Satoshi ; Iwata, Sokichi ; Miyakoshi, Kei. / Abnormal first-trimester fetal nuchal translucency and amniotic band syndrome. In: Journal of Medical Ultrasonics. 2012 ; Vol. 39, No. 3. pp. 177-180.
@article{e5228d64349340129af9b629345118cf,
title = "Abnormal first-trimester fetal nuchal translucency and amniotic band syndrome",
abstract = "We report a case of amniotic band syndrome diagnosed prenatally by serial sonographic examinations. Our initial sonographic image showed a large fetal nuchal translucency (NT) at 12 weeks' gestation. Repeated fetal ultrasound images revealed an amniotic band and right upper limb anomaly. Fetal MRI at 19 weeks' gestation revealed right forearm hypoplasia and pseudosyndactyly. The fetus was prenatally diagnosed with amniotic band syndrome and was suspected of having severe functional impairment of the deformed limb. The parents decided to terminate the pregnancy at 21 weeks' gestation. In fetuses with aneuploidy and various structural and genetic abnormalities, the NT thickness is increased in the first trimester. As far as we are aware, this is the first case report of increased NT and limb anomaly associated with amniotic band syndrome. In chromosomally normal fetuses with increased NT, intensive sonographic follow-up should provide grounds for a precise antenatal diagnosis.",
keywords = "Amniotic band syndrome, Nuchal translucency",
author = "Takayuki Higuchi and Mamoru Tanaka and Keiko Kuroda and Akira Yabuno and Kim, {Seon Hye} and Satoshi Asai and Sokichi Iwata and Kei Miyakoshi",
year = "2012",
month = "7",
doi = "10.1007/s10396-012-0344-0",
language = "English",
volume = "39",
pages = "177--180",
journal = "Japanese Journal of Medical Ultrasonics",
issn = "1346-4523",
publisher = "Springer Japan",
number = "3",

}

TY - JOUR

T1 - Abnormal first-trimester fetal nuchal translucency and amniotic band syndrome

AU - Higuchi, Takayuki

AU - Tanaka, Mamoru

AU - Kuroda, Keiko

AU - Yabuno, Akira

AU - Kim, Seon Hye

AU - Asai, Satoshi

AU - Iwata, Sokichi

AU - Miyakoshi, Kei

PY - 2012/7

Y1 - 2012/7

N2 - We report a case of amniotic band syndrome diagnosed prenatally by serial sonographic examinations. Our initial sonographic image showed a large fetal nuchal translucency (NT) at 12 weeks' gestation. Repeated fetal ultrasound images revealed an amniotic band and right upper limb anomaly. Fetal MRI at 19 weeks' gestation revealed right forearm hypoplasia and pseudosyndactyly. The fetus was prenatally diagnosed with amniotic band syndrome and was suspected of having severe functional impairment of the deformed limb. The parents decided to terminate the pregnancy at 21 weeks' gestation. In fetuses with aneuploidy and various structural and genetic abnormalities, the NT thickness is increased in the first trimester. As far as we are aware, this is the first case report of increased NT and limb anomaly associated with amniotic band syndrome. In chromosomally normal fetuses with increased NT, intensive sonographic follow-up should provide grounds for a precise antenatal diagnosis.

AB - We report a case of amniotic band syndrome diagnosed prenatally by serial sonographic examinations. Our initial sonographic image showed a large fetal nuchal translucency (NT) at 12 weeks' gestation. Repeated fetal ultrasound images revealed an amniotic band and right upper limb anomaly. Fetal MRI at 19 weeks' gestation revealed right forearm hypoplasia and pseudosyndactyly. The fetus was prenatally diagnosed with amniotic band syndrome and was suspected of having severe functional impairment of the deformed limb. The parents decided to terminate the pregnancy at 21 weeks' gestation. In fetuses with aneuploidy and various structural and genetic abnormalities, the NT thickness is increased in the first trimester. As far as we are aware, this is the first case report of increased NT and limb anomaly associated with amniotic band syndrome. In chromosomally normal fetuses with increased NT, intensive sonographic follow-up should provide grounds for a precise antenatal diagnosis.

KW - Amniotic band syndrome

KW - Nuchal translucency

UR - http://www.scopus.com/inward/record.url?scp=84863877634&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863877634&partnerID=8YFLogxK

U2 - 10.1007/s10396-012-0344-0

DO - 10.1007/s10396-012-0344-0

M3 - Article

VL - 39

SP - 177

EP - 180

JO - Japanese Journal of Medical Ultrasonics

JF - Japanese Journal of Medical Ultrasonics

SN - 1346-4523

IS - 3

ER -