Absolute risk for fracture and WHO guideline. Biological markers for osteoarthritis (OA)

Hideki Date, Harumoto Yamada, Arihiko Kanaji, Kaori Tajima, Kazue Hayakawa, Kazuyuki Maehara, Kyosuke Miyazaki, Hiroyuki Masuda

Research output: Contribution to journalReview article

Abstract

Biological markers for osteoarthritis (OA) are indicators of articular tissue metabolism, measuring the levels of molecules derived from joint structures into synovial fluids, serum and urine. Radiological findings are the basis of diagnosis of OA, but have a weakpoint visualizing the figures that have already occurred. For assessing disease activity or monitoring disease progression, estimation of articular metabolism using biological markers is very important. Synovial fluid reflects specifically the status of the punctured joint, however invasive. Less-invasive newly developed serum and urine markers appear to be also useful for the evaluation of OA.

Original languageEnglish
Pages (from-to)1071-1079
Number of pages9
JournalClinical calcium
Volume17
Issue number7
Publication statusPublished - 2007 Jul
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Date, H., Yamada, H., Kanaji, A., Tajima, K., Hayakawa, K., Maehara, K., Miyazaki, K., & Masuda, H. (2007). Absolute risk for fracture and WHO guideline. Biological markers for osteoarthritis (OA). Clinical calcium, 17(7), 1071-1079.