Acacia concinna saponins. I. Structures of prosapogenols, concinnosides A-F, isolated from the alkaline hydrolysate of the highly polar saponin fraction

Mohammod Abdul Gafur; Tohoru Obata; Fumiyuki Kiuchi; Yoshisuke Tsuda

doi:10.1248/cpb.45.620

Acacia concinna saponins. I. Structures of prosapogenols, concinnosides A-F, isolated from the alkaline hydrolysate of the highly polar saponin fraction

Mohammod Abdul Gafur, Tohoru Obata, Fumiyuki Kiuchi, Yoshisuke Tsuda

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

A highly polar saponin mixture from pods of Acacia concinna (Leguminosae) was hydrolyzed with alkali to yield five new triterpenoidal prosapogenols named concinnosides A (6), B (3), C (7), D (4), and E (8), together with four known glycosides, acaciaside (2), julibroside A₁ (10), julibroside A₃ (9), albiziasaponin C (5), and their aglycone, acacic acid lactone (1). The structures of these new prosapogenols were elucidated based on spectroscopic means. A less polar saponin fraction from the pods gave spinasteryl glucoside and its dihydro derivative.

Original language	English
Pages (from-to)	620-625
Number of pages	6
Journal	Chemical and Pharmaceutical Bulletin
Volume	45
Issue number	4
DOIs	https://doi.org/10.1248/cpb.45.620
Publication status	Published - 1997 Apr
Externally published	Yes

Keywords

Acacia concinna
acacic acid lactone
alkaline hydrolysis
concinnoside
prosapogenol
spinasteryl glucoside

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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Acacia concinna saponins. I. Structures of prosapogenols, concinnosides A-F, isolated from the alkaline hydrolysate of the highly polar saponin fraction. / Gafur, Mohammod Abdul; Obata, Tohoru; Kiuchi, Fumiyuki; Tsuda, Yoshisuke.

In: Chemical and Pharmaceutical Bulletin, Vol. 45, No. 4, 04.1997, p. 620-625.

Research output: Contribution to journal › Article › peer-review

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abstract = "A highly polar saponin mixture from pods of Acacia concinna (Leguminosae) was hydrolyzed with alkali to yield five new triterpenoidal prosapogenols named concinnosides A (6), B (3), C (7), D (4), and E (8), together with four known glycosides, acaciaside (2), julibroside A1 (10), julibroside A3 (9), albiziasaponin C (5), and their aglycone, acacic acid lactone (1). The structures of these new prosapogenols were elucidated based on spectroscopic means. A less polar saponin fraction from the pods gave spinasteryl glucoside and its dihydro derivative.",

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AU - Obata, Tohoru

AU - Kiuchi, Fumiyuki

AU - Tsuda, Yoshisuke

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N2 - A highly polar saponin mixture from pods of Acacia concinna (Leguminosae) was hydrolyzed with alkali to yield five new triterpenoidal prosapogenols named concinnosides A (6), B (3), C (7), D (4), and E (8), together with four known glycosides, acaciaside (2), julibroside A1 (10), julibroside A3 (9), albiziasaponin C (5), and their aglycone, acacic acid lactone (1). The structures of these new prosapogenols were elucidated based on spectroscopic means. A less polar saponin fraction from the pods gave spinasteryl glucoside and its dihydro derivative.

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KW - acacic acid lactone

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KW - concinnoside

KW - prosapogenol

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Acacia concinna saponins. I. Structures of prosapogenols, concinnosides A-F, isolated from the alkaline hydrolysate of the highly polar saponin fraction

Abstract

Keywords

ASJC Scopus subject areas

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