Abstract
From the AcOEt-soluble fraction of the alkaline hydrolyzate of the highly polar saponin fraction of pods of Acacia concinna, two monoterpenes, (2E)-2,6-dimethyl-6-hydroxy-2,7-octadienoic acid (menthiafolic acid, 1) and (2E)-6-hydroxy-2-hydroxymethyl-6-methyl-2,7-octadienoic acid (4), and their glycosides, (6R)- and (6S)-menthiafolic acid-6-O-β-D-quinovoside (2a and 2b) and (6R)- and (6S)-menthiafolic acid-6-O-β-D-xyloside (3a and 3b), were isolated. A more polar fraction gave, after methylation with diazomethane, (6R)- and (6S)-(2E)-6-hydroxy-2-hydroxymethyl-6-methyl-2,7-octadienoic acid- 6-O-β-D-quinovoside as their methyl esters (5a and 5b). Compounds 2a, 3a, 4, 5a, and 5b are new. The structures of the above compounds were determined mainly by the application of spectroscopic methods.
Original language | English |
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Pages (from-to) | 807-812 |
Number of pages | 6 |
Journal | Chemical and Pharmaceutical Bulletin |
Volume | 45 |
Issue number | 5 |
DOIs | |
Publication status | Published - 1997 May |
Externally published | Yes |
Keywords
- Acacia concinna
- C-NMR
- Menthiafolic acid
- Monoterpene glycoside
- β-D- quinovoside
- β-D-xyloside
ASJC Scopus subject areas
- Chemistry(all)
- Drug Discovery