Accelerated tumor growth and changes in images concomitant with vascularization in a patient with hepatocellular carcinoma

N. Okazaki, T. Kosuge, T. Takayama, S. Okada, M. Yoshino, K. Takayasu, N. Moriyama, M. Sakamoto, S. Hirohashi

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Abstract

We examined serial changes of tumor images in a patient with hepatocellular carcinoma. The hepatocellular carcinoma was initially detected as a homogeneous low-echo area with unclear margins, which was not enhanced by contrast media on computed tomograms, and did not reveal any vascular abnormalities on hepatic angiography. About 11 months later, the tumor growth accelerated, with a parallel increase in serum alpha-fetoprotein levels, and the ultrasonographic features of the tumor changed from a homogeneous low-echo area to a mixed low- and high-echo area with a peripheral low-echo zone. Hepatic angiography revealed a hypervascular tumor at this time. The present case indicates that tumor growth and imaging patterns of hepatocellular carcinoma are closely related to vascularization of the tumor.

Original languageEnglish
Pages (from-to)160-164
Number of pages5
JournalHepato-gastroenterology
Volume38
Issue number2
Publication statusPublished - 1991 Jan 1
Externally publishedYes

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Keywords

  • hepatocellular carcinoma
  • imaging diagnosis
  • tumor growth
  • vascularization

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Okazaki, N., Kosuge, T., Takayama, T., Okada, S., Yoshino, M., Takayasu, K., Moriyama, N., Sakamoto, M., & Hirohashi, S. (1991). Accelerated tumor growth and changes in images concomitant with vascularization in a patient with hepatocellular carcinoma. Hepato-gastroenterology, 38(2), 160-164.