Action of nitrile hydratase from rhodococcus rhodochrous IFO 15564 on Derivatives of 2,5-Anhydro-d-allononitrile

Masahiro Yokoyama, Yuko Nakatsuka, Takeshi Sugai, Hiromichi Ohta

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

The conversion of 2,5-anhydro-d-allononitrile derivatives by a nitrile hydratase from Rhodococcus rhodochrous IFO 15564 was studied. The activity of the enzyme was strongly effected by the steric bulkiness of the substituents at the 3-position of the substrates, and the corresponding amides were obtained in high yields from the nitriles with free hydroxyl groups at the 3- and 4-positions.

Original languageEnglish
Pages (from-to)1540-1542
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume60
Issue number9
DOIs
Publication statusPublished - 1996 Jan

Keywords

  • 2,5-anhydro-d-allonamide
  • 2,5-anhydro-d-allononitrile
  • Hydantocidin
  • Nitrile hydratase
  • Rhodococcus rhodochrous IFO 15564

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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