Actomyosin-collagen hybrid soft actuator

Kenjiro Kohno, Shusei Kwara, Yuichi Hiratsuka, Hiroaki Onoe

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Soft actuators mimicking biological muscles have been built by polymerizing actin and myosin in vitro to construct actomyosin, however, the mechanical strength of the actomyosin was generally not sufficient for practical uses as an actuator. In this study, we proposed an actomyosin-collagen hybrid actuator with high mechanical strength and formability by reconstructing actomyosin biomolecular linear motors inside collagen gel matrix. This actuator can be contracted by adding ATP and returned to its original length by applying an external tensile force, resulting that the actuator could be driven multiple times. This actuator could be expected as an actuator for environment-friendly micro-robots and wearable medical devices.

Original languageEnglish
Title of host publicationMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages997-998
Number of pages2
ISBN (Electronic)9781733419017
Publication statusPublished - 2020
Event24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 - Virtual, Online
Duration: 2020 Oct 42020 Oct 9

Publication series

NameMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
CityVirtual, Online
Period20/10/420/10/9

Keywords

  • Actin
  • Actomyosin
  • Collagen
  • Motor protein
  • Myosin
  • Soft actuator

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering
  • Chemistry(all)
  • Control and Systems Engineering

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