Acute exacerbation of subacute interstitial pneumonia after thoracoscopic lung biopsy

S. Tasaka, M. Kanazawa, Y. Komune, Kenzo Soejima, Michito Hirakata, K. Yamaguchi, M. Naruke, M. Mukai, Y. Kawabata, K. Kobayashi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A 55-year-old woman was admitted to our hospital with progressive dyspnea that had begun one month before. Chest rentogenogram revealed groundglass appearance and reticular shadows bilaterally. Pulmonary function tests showed both decreased vital capacity and diffusing capacity. Bronchoalveolar lavage fluid had a high lymphocyte fraction with a low CD4+/CD8+ ratio. Thoracoscopic lung biopsy revealed thick, fibro-edematous interstitium and diffuse infiltration of lymphocytes. We also observed an intra-alveolar exudate with infiltration of histiocytes and lymphocytes. The clinical features and pathological findings were consistent with subacute interstitial pneumonia, which was the entity proposed by Kawabata and colleagues. The patient developed acute respiratory failure four days after lung biopsy and died despite steroid pulse therapy. Although subacute interstitial pneumonia has been reported to respond to steroid therapy, and to have a good prognosis, we believe that subacute interstitial pneumonia could fatally worsen when associated with lung biopsy, infection, or some other stimulus.

Original languageEnglish
Pages (from-to)182-186
Number of pages5
JournalNihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
Volume36
Issue number2
Publication statusPublished - 1998

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Interstitial Lung Diseases
Lymphocytes
Biopsy
Lung
Steroids
CD4-CD8 Ratio
Histiocytes
Respiratory Function Tests
Vital Capacity
Bronchoalveolar Lavage Fluid
Exudates and Transudates
Respiratory Insufficiency
Dyspnea
Thorax
Therapeutics
Infection

Cite this

Acute exacerbation of subacute interstitial pneumonia after thoracoscopic lung biopsy. / Tasaka, S.; Kanazawa, M.; Komune, Y.; Soejima, Kenzo; Hirakata, Michito; Yamaguchi, K.; Naruke, M.; Mukai, M.; Kawabata, Y.; Kobayashi, K.

In: Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society, Vol. 36, No. 2, 1998, p. 182-186.

Research output: Contribution to journalArticle

Tasaka, S, Kanazawa, M, Komune, Y, Soejima, K, Hirakata, M, Yamaguchi, K, Naruke, M, Mukai, M, Kawabata, Y & Kobayashi, K 1998, 'Acute exacerbation of subacute interstitial pneumonia after thoracoscopic lung biopsy', Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society, vol. 36, no. 2, pp. 182-186.
Tasaka, S. ; Kanazawa, M. ; Komune, Y. ; Soejima, Kenzo ; Hirakata, Michito ; Yamaguchi, K. ; Naruke, M. ; Mukai, M. ; Kawabata, Y. ; Kobayashi, K. / Acute exacerbation of subacute interstitial pneumonia after thoracoscopic lung biopsy. In: Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society. 1998 ; Vol. 36, No. 2. pp. 182-186.
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AU - Kanazawa, M.

AU - Komune, Y.

AU - Soejima, Kenzo

AU - Hirakata, Michito

AU - Yamaguchi, K.

AU - Naruke, M.

AU - Mukai, M.

AU - Kawabata, Y.

AU - Kobayashi, K.

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