Adhesion behaviors of Escherichia coli on hydroxyapatite

Masanobu Kamitakahara, Shohei Takahashi, Taishi Yokoi, Chihiro Inoue, Koji Ioku

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


Optimum design of support materials for microorganisms is required for the construction of bioreactors. However, the effects of support materials on microorganisms are still unclear. In this study, we investigated the adhesion behavior of Escherichia coli (E. coli) on hydroxyapatite (HA), polyurethane (PU), poly(vinyl chloride) (PVC), and carbon (Carbon) to obtain basic knowledge for the design of support materials. The total metabolic activity and number of E. coli adhering on the samples followed the order of HA ≈Carbon > PVC > PU. On the other hand, the water contact angle of the pellet surfaces followed the order of HA < Carbon < PVC < PU. The high hydrophilicity of the HA surface might be one of the suitable characters for the adhesion of E. coli. The results implied that HA has a potential as a support material for microorganisms used in bioreactors.

Original languageEnglish
Pages (from-to)169-173
Number of pages5
JournalMaterials Science and Engineering C
Publication statusPublished - 2016 Apr 1


  • Adhesion
  • Escherichia coli
  • Hydroxyapatite
  • Support material

ASJC Scopus subject areas

  • Bioengineering
  • Biomaterials


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