Adiponectin in chronic thromboembolic pulmonary hypertension

Sarasa Isobe, Masaharu Kataoka, Takashi Kawakami, Keiichi Fukuda

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: The correlation between serum adiponectin concentration and hemodynamics or certain metabolic markers in patients with chronic thromboembolic pulmonary hypertension (CTEPH) is unknown. Methods and Results: We enrolled 30 CTEPH patients who underwent interventional therapy of balloon pulmonary angioplasty or pulmonary endarterectomy. Serum adiponectin concentrations positively correlated with B-type natriuretic peptide (BNP) concentrations, pulmonary vascular resistance, and mean pulmonary arterial pressure. After the therapeutic interventions, serum adiponectin concentrations improved and changes in serum adiponectin concentrations significantly correlated with changes in BNP concentrations. Conclusions: Adiponectin can be a useful marker for the severity of CTEPH.

Original languageEnglish
Pages (from-to)1466-1468
Number of pages3
JournalCirculation Journal
Volume82
Issue number5
DOIs
Publication statusPublished - 2018 Jan 1

Fingerprint

Adiponectin
Pulmonary Hypertension
Brain Natriuretic Peptide
Serum
Lung
Endarterectomy
Balloon Angioplasty
Vascular Resistance
Arterial Pressure
Hemodynamics
Therapeutics

Keywords

  • Adiponectin
  • B-type natriuretic peptide
  • Chronic thromboembolic pulmonary hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Adiponectin in chronic thromboembolic pulmonary hypertension. / Isobe, Sarasa; Kataoka, Masaharu; Kawakami, Takashi; Fukuda, Keiichi.

In: Circulation Journal, Vol. 82, No. 5, 01.01.2018, p. 1466-1468.

Research output: Contribution to journalArticle

Isobe, Sarasa ; Kataoka, Masaharu ; Kawakami, Takashi ; Fukuda, Keiichi. / Adiponectin in chronic thromboembolic pulmonary hypertension. In: Circulation Journal. 2018 ; Vol. 82, No. 5. pp. 1466-1468.
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