Adjuvant pelvic irradiation in patients with node-negative carcinoma of the uterine cervix

Takashi Uno, Hisao Ito, Shigeo Yasuda, Takashi Aruga, Koichi Isobe, Hiroyuki Kawakami, Akira Mitsuhashi, Naotake Tanaka, Kouji Yamazawa, Kiyomi Suzuka, Souei Sekiya, Jun Itami, Naoyuki Shigematsu, Atsushi Kubo

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: To assess the role of post-operative pelvic radiotherapy in cervical cancer patients without lymph node metastases. Materials and Methods: The records of 61 patients with cervical cancer treated with radical hysterectomy and bilateral pelvic lymphadenectomy followed by pelvic irradiation were reviewed. The distribution of FIGO stage was IB in 34, IIA in 5 and IIB in 22. The patients were treated with 10-18 MV X-rays using a fractional daily dose of 1.8-2.0 Gy to a median total dose of 50 Gy. Results: The actuarial 5-year pelvic control rate was 95%. There was no isolated pelvic lymph node recurrence. The overall 5-year survival of the entire group was 89%. The mean age of the patients who developed recurrence was lower than the other patients (46 years vs. 53 years, p=0.07). Conclusion: The results indicated that post-operative pelvic irradiation was effective in preventing pelvic recurrence in patients with node-negative cervical cancer.

Original languageEnglish
Pages (from-to)1213-1216
Number of pages4
JournalAnticancer Research
Volume22
Issue number2 B
Publication statusPublished - 2002
Externally publishedYes

Fingerprint

Cervix Uteri
Carcinoma
Uterine Cervical Neoplasms
Recurrence
Lymph Nodes
Lymph Node Excision
Hysterectomy
Radiotherapy
X-Rays
Neoplasm Metastasis
Survival

Keywords

  • Carcinoma
  • Negative pelvic node
  • Post-operative radiation therapy
  • Uterine cervix

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Uno, T., Ito, H., Yasuda, S., Aruga, T., Isobe, K., Kawakami, H., ... Kubo, A. (2002). Adjuvant pelvic irradiation in patients with node-negative carcinoma of the uterine cervix. Anticancer Research, 22(2 B), 1213-1216.

Adjuvant pelvic irradiation in patients with node-negative carcinoma of the uterine cervix. / Uno, Takashi; Ito, Hisao; Yasuda, Shigeo; Aruga, Takashi; Isobe, Koichi; Kawakami, Hiroyuki; Mitsuhashi, Akira; Tanaka, Naotake; Yamazawa, Kouji; Suzuka, Kiyomi; Sekiya, Souei; Itami, Jun; Shigematsu, Naoyuki; Kubo, Atsushi.

In: Anticancer Research, Vol. 22, No. 2 B, 2002, p. 1213-1216.

Research output: Contribution to journalArticle

Uno, T, Ito, H, Yasuda, S, Aruga, T, Isobe, K, Kawakami, H, Mitsuhashi, A, Tanaka, N, Yamazawa, K, Suzuka, K, Sekiya, S, Itami, J, Shigematsu, N & Kubo, A 2002, 'Adjuvant pelvic irradiation in patients with node-negative carcinoma of the uterine cervix', Anticancer Research, vol. 22, no. 2 B, pp. 1213-1216.
Uno T, Ito H, Yasuda S, Aruga T, Isobe K, Kawakami H et al. Adjuvant pelvic irradiation in patients with node-negative carcinoma of the uterine cervix. Anticancer Research. 2002;22(2 B):1213-1216.
Uno, Takashi ; Ito, Hisao ; Yasuda, Shigeo ; Aruga, Takashi ; Isobe, Koichi ; Kawakami, Hiroyuki ; Mitsuhashi, Akira ; Tanaka, Naotake ; Yamazawa, Kouji ; Suzuka, Kiyomi ; Sekiya, Souei ; Itami, Jun ; Shigematsu, Naoyuki ; Kubo, Atsushi. / Adjuvant pelvic irradiation in patients with node-negative carcinoma of the uterine cervix. In: Anticancer Research. 2002 ; Vol. 22, No. 2 B. pp. 1213-1216.
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AU - Yasuda, Shigeo

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AU - Kawakami, Hiroyuki

AU - Mitsuhashi, Akira

AU - Tanaka, Naotake

AU - Yamazawa, Kouji

AU - Suzuka, Kiyomi

AU - Sekiya, Souei

AU - Itami, Jun

AU - Shigematsu, Naoyuki

AU - Kubo, Atsushi

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N2 - Background: To assess the role of post-operative pelvic radiotherapy in cervical cancer patients without lymph node metastases. Materials and Methods: The records of 61 patients with cervical cancer treated with radical hysterectomy and bilateral pelvic lymphadenectomy followed by pelvic irradiation were reviewed. The distribution of FIGO stage was IB in 34, IIA in 5 and IIB in 22. The patients were treated with 10-18 MV X-rays using a fractional daily dose of 1.8-2.0 Gy to a median total dose of 50 Gy. Results: The actuarial 5-year pelvic control rate was 95%. There was no isolated pelvic lymph node recurrence. The overall 5-year survival of the entire group was 89%. The mean age of the patients who developed recurrence was lower than the other patients (46 years vs. 53 years, p=0.07). Conclusion: The results indicated that post-operative pelvic irradiation was effective in preventing pelvic recurrence in patients with node-negative cervical cancer.

AB - Background: To assess the role of post-operative pelvic radiotherapy in cervical cancer patients without lymph node metastases. Materials and Methods: The records of 61 patients with cervical cancer treated with radical hysterectomy and bilateral pelvic lymphadenectomy followed by pelvic irradiation were reviewed. The distribution of FIGO stage was IB in 34, IIA in 5 and IIB in 22. The patients were treated with 10-18 MV X-rays using a fractional daily dose of 1.8-2.0 Gy to a median total dose of 50 Gy. Results: The actuarial 5-year pelvic control rate was 95%. There was no isolated pelvic lymph node recurrence. The overall 5-year survival of the entire group was 89%. The mean age of the patients who developed recurrence was lower than the other patients (46 years vs. 53 years, p=0.07). Conclusion: The results indicated that post-operative pelvic irradiation was effective in preventing pelvic recurrence in patients with node-negative cervical cancer.

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KW - Post-operative radiation therapy

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