Adjuvant pelvic irradiation in patients with node-negative carcinoma of the uterine cervix

Takashi Uno, Hisao Ito, Shigeo Yasuda, Takashi Aruga, Koichi Isobe, Hiroyuki Kawakami, Akira Mitsuhashi, Naotake Tanaka, Kouji Yamazawa, Kiyomi Suzuka, Souei Sekiya, Jun Itami, Naoyuki Shigematsu, Atsushi Kubo

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Background: To assess the role of post-operative pelvic radiotherapy in cervical cancer patients without lymph node metastases. Materials and Methods: The records of 61 patients with cervical cancer treated with radical hysterectomy and bilateral pelvic lymphadenectomy followed by pelvic irradiation were reviewed. The distribution of FIGO stage was IB in 34, IIA in 5 and IIB in 22. The patients were treated with 10-18 MV X-rays using a fractional daily dose of 1.8-2.0 Gy to a median total dose of 50 Gy. Results: The actuarial 5-year pelvic control rate was 95%. There was no isolated pelvic lymph node recurrence. The overall 5-year survival of the entire group was 89%. The mean age of the patients who developed recurrence was lower than the other patients (46 years vs. 53 years, p=0.07). Conclusion: The results indicated that post-operative pelvic irradiation was effective in preventing pelvic recurrence in patients with node-negative cervical cancer.

Original languageEnglish
Pages (from-to)1213-1216
Number of pages4
JournalAnticancer research
Volume22
Issue number2 B
Publication statusPublished - 2002 Aug 13
Externally publishedYes

Keywords

  • Carcinoma
  • Negative pelvic node
  • Post-operative radiation therapy
  • Uterine cervix

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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