Administration of teriparatide treatment for a challenging case of nonunion of periprosthetic fracture after total knee arthroplasty

Kensuke Ochi, Katsunori Ikari, Akari Naomi, Shigeki Momohara

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Introduction: Management of a periprosthetic fracture after total knee arthroplasty is often challenging because it typically occurs in elderly patients, who often have osteoporotic bone with a high risk of delayed union and nonunion. Thus, administration of a medication that could effectively accelerate fracture healing to prevent a delayed union or nonunion should significantly improve treatment outcome and patient's quality of life. Case presentation: We report the case of a 74-year-old rheumatoid arthritis woman with nonunion of a periprosthetic fracture after total knee arthroplasty, in whom bone union could not be achieved even after she underwent internal fixation and bone grafting twice; however, successful bone fusion was achieved after simple once-weekly administration of teriparatide for 6 months. Discussion: Although we report only one patient, the present case may suggest the advantage of preventive administration of teriparatide in addition to surgical procedures for treating nonunion of a periprosthetic fracture after total knee arthroplasty.

Original languageEnglish
Article number159
JournalArchives of Osteoporosis
Volume8
Issue number1-2
DOIs
Publication statusPublished - 2013
Externally publishedYes

Fingerprint

Periprosthetic Fractures
Teriparatide
Knee Replacement Arthroplasties
Bone and Bones
Fracture Healing
Bone Transplantation
Rheumatoid Arthritis
Therapeutics
Quality of Life

Keywords

  • Delayed union
  • Nonunion
  • Periprosthetic fracture
  • Rheumatoid arthritis
  • Teriparatide
  • Total knee arthroplasty

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Medicine(all)

Cite this

Administration of teriparatide treatment for a challenging case of nonunion of periprosthetic fracture after total knee arthroplasty. / Ochi, Kensuke; Ikari, Katsunori; Naomi, Akari; Momohara, Shigeki.

In: Archives of Osteoporosis, Vol. 8, No. 1-2, 159, 2013.

Research output: Contribution to journalArticle

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