Adult head modelling based on time-resolved measurement for NIR instrument

S. Misonoo, Eiji Okada

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

The accurate forward modelling of light propagation in tissue to estimate the partial optical path length in the brain is important for quantitative optical spectroscopy and optical imaging. In this study design of simplified adult head model is investigated to estimate the partial optical path length in the brain. We consider homogeneous, two and three layered models as the simplified models. The apparent optical properties of surface layer of the simplified model are determined by TPSFs at small source-detector separations. Since it is difficult to determine the optical properties of the brain from the in-vivo time-resolved measurement, the optical properties of the brain are assumed to be the reported data. The proposed modelling is evaluated by Monte Carlo simulation. The TPSFs of the five layered models that consist of the scalp, skull, CSF, grey matter and white matter are predicted by Monte Carlo simulation. The apparent optical properties of the surface layer are estimated from the TPSFs for five layered adult head model, and the partial optical path length in the brain is predicted from the proposed simplified models. The predicted partial optical path length is compared with that calculated from the five layered model to evaluate the proposed modelling.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsB. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, E.M. Sevick-Muraka
Pages522-529
Number of pages8
Volume4250
DOIs
Publication statusPublished - 2001
EventOptical Tomography and Spectroscopy of Tissue IV - San Jose, CA, United States
Duration: 2001 Jan 212001 Jan 23

Other

OtherOptical Tomography and Spectroscopy of Tissue IV
CountryUnited States
CitySan Jose, CA
Period01/1/2101/1/23

Fingerprint

Time measurement
time measurement
brain
Brain
optical paths
Optical properties
optical properties
surface layers
skull
Light propagation
estimates
simulation
Tissue
Detectors
Imaging techniques
propagation
detectors
spectroscopy

Keywords

  • Monte Carlo simulation
  • Optical properties
  • Partial mean optical path length
  • Time-resolved measurement

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Misonoo, S., & Okada, E. (2001). Adult head modelling based on time-resolved measurement for NIR instrument. In B. Chance, R. R. Alfano, B. J. Tromberg, M. Tamura, & E. M. Sevick-Muraka (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4250, pp. 522-529) https://doi.org/10.1117/12.434527

Adult head modelling based on time-resolved measurement for NIR instrument. / Misonoo, S.; Okada, Eiji.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / B. Chance; R.R. Alfano; B.J. Tromberg; M. Tamura; E.M. Sevick-Muraka. Vol. 4250 2001. p. 522-529.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Misonoo, S & Okada, E 2001, Adult head modelling based on time-resolved measurement for NIR instrument. in B Chance, RR Alfano, BJ Tromberg, M Tamura & EM Sevick-Muraka (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 4250, pp. 522-529, Optical Tomography and Spectroscopy of Tissue IV, San Jose, CA, United States, 01/1/21. https://doi.org/10.1117/12.434527
Misonoo S, Okada E. Adult head modelling based on time-resolved measurement for NIR instrument. In Chance B, Alfano RR, Tromberg BJ, Tamura M, Sevick-Muraka EM, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4250. 2001. p. 522-529 https://doi.org/10.1117/12.434527
Misonoo, S. ; Okada, Eiji. / Adult head modelling based on time-resolved measurement for NIR instrument. Proceedings of SPIE - The International Society for Optical Engineering. editor / B. Chance ; R.R. Alfano ; B.J. Tromberg ; M. Tamura ; E.M. Sevick-Muraka. Vol. 4250 2001. pp. 522-529
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