TY - JOUR
T1 - Advances in hematopoietic stem cell transplantation in the Asia-Pacific region
T2 - the second report from APBMT 2005–2015
AU - Registry Committee of the Asia-Pacific Blood and Marrow Transplantation Group (APBMT)
AU - Iida, Minako
AU - Kodera, Yoshihisa
AU - Dodds, Anthony
AU - Ho, Aloysius Yew Leng
AU - Nivison-Smith, Ian
AU - Akter, Mafruha Rumana
AU - Wu, Tong
AU - Lie, Albert Kwok Wai
AU - Ghavamzadeh, Ardeshir
AU - Kang, Hyoung Jin
AU - Ong, Tee Chuan
AU - Gyi, Aye Aye
AU - Farzana, Tasneem
AU - Baylon, Honorata
AU - Gooneratne, Lallindra
AU - Tang, Jih Luh
AU - Bunworasate, Udomsak
AU - Huynh, Van Man
AU - Srivastava, Alok
AU - Okamoto, Shinichiro
AU - Atsuta, Yoshiko
N1 - Funding Information:
Acknowledgements We are grateful to all APBMT members, especially to all Scientific Committee members and their data managers who gathered data in each registry, country, center, or hospital every year. The cooperation of all participating teams, countries/regions and organizations with their staff is greatly appreciated, in particular, the ABMTRR, ISCTR, KSBMT, JSHCT/JDCHCT, and TBMT. This report was supported by the APBMT Registry Committee and Data Center. We also thank Yukari Nakao and Hiroe Namizaki of the APBMT Data Center for their data management. The secretarial assistance of Haruko Nakamura is also appreciated.
Publisher Copyright:
© 2019, Springer Nature Limited.
PY - 2019/12/1
Y1 - 2019/12/1
N2 - Between 2005 and 2015, 138,165 hematopoietic stem cell transplantation (HSCT) were reported in 18 countries/regions in the Asia-Pacific region. In this report, we describe current trends in HSCT throughout the Asia-Pacific region and differences among nations in this region and various global registries. Since 2008, more than 10,000 HSCTs have been recorded each year by the Asia-Pacific Blood and Marrow Transplantation Group Data Center. Between 2005 and 2015, the greatest increase in the number of HSCTs was observed in Vietnam. Allogeneic HSCT was performed more frequently than autologous HSCT, and a majority of cases involved related donors. Regarding allogeneic HSCT, the use of cord blood has remained steady, especially in Japan, and the number of cases involving related HLA non-identical donors has increased rapidly, particularly in China. The incidence of hemoglobinopathy, a main indication for allogeneic HSCT in India, China, Iran, and Pakistan, increased nearly six-fold over the last decade. Among the 18 participating countries/regions, the transplant rate per population varied widely according to the absolute number of HSCTs and the national/regional population size. We believe that this report will not only benefit the AP region but will also provide information about HSCT to other regions worldwide.
AB - Between 2005 and 2015, 138,165 hematopoietic stem cell transplantation (HSCT) were reported in 18 countries/regions in the Asia-Pacific region. In this report, we describe current trends in HSCT throughout the Asia-Pacific region and differences among nations in this region and various global registries. Since 2008, more than 10,000 HSCTs have been recorded each year by the Asia-Pacific Blood and Marrow Transplantation Group Data Center. Between 2005 and 2015, the greatest increase in the number of HSCTs was observed in Vietnam. Allogeneic HSCT was performed more frequently than autologous HSCT, and a majority of cases involved related donors. Regarding allogeneic HSCT, the use of cord blood has remained steady, especially in Japan, and the number of cases involving related HLA non-identical donors has increased rapidly, particularly in China. The incidence of hemoglobinopathy, a main indication for allogeneic HSCT in India, China, Iran, and Pakistan, increased nearly six-fold over the last decade. Among the 18 participating countries/regions, the transplant rate per population varied widely according to the absolute number of HSCTs and the national/regional population size. We believe that this report will not only benefit the AP region but will also provide information about HSCT to other regions worldwide.
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U2 - 10.1038/s41409-019-0554-9
DO - 10.1038/s41409-019-0554-9
M3 - Article
C2 - 31089289
AN - SCOPUS:85065924078
VL - 54
SP - 1973
EP - 1986
JO - Bone Marrow Transplantation
JF - Bone Marrow Transplantation
SN - 0268-3369
IS - 12
ER -