Age-dependent chemosensitive pontine inhibition of medullary respiratory rhythm generation in the isolated brainstem of the neonatal rat

Yoko Ito, Yoshitaka Oyamada, Kazuhiro Yamaguchi

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Age-dependence and chemosensitivity of the pontine inhibitory effect on medullary respiratory rhythm generation were examined in the isolated brainstem-spinal cord of the neonatal rat. In early preparations (days 1-2), the increase in RR (ΔRR) induced by the pons resection was larger in 8% CO2 (pH 7.2) than in 2% CO2 (pH 7.8). That difference was not found in late preparations (days 3-4). Under a given pH, the ΔRR was larger in early preparations than in late preparations.

Original languageEnglish
Pages (from-to)418-420
Number of pages3
JournalBrain Research
Volume887
Issue number2
DOIs
Publication statusPublished - 2000 Dec 29

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Brain Stem
Pons
Spinal Cord

Keywords

  • A5 neurones
  • Chemosensitivity
  • Locus coeruleus
  • Medulla
  • Pons
  • Respiration

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Age-dependent chemosensitive pontine inhibition of medullary respiratory rhythm generation in the isolated brainstem of the neonatal rat. / Ito, Yoko; Oyamada, Yoshitaka; Yamaguchi, Kazuhiro.

In: Brain Research, Vol. 887, No. 2, 29.12.2000, p. 418-420.

Research output: Contribution to journalArticle

Ito, Yoko ; Oyamada, Yoshitaka ; Yamaguchi, Kazuhiro. / Age-dependent chemosensitive pontine inhibition of medullary respiratory rhythm generation in the isolated brainstem of the neonatal rat. In: Brain Research. 2000 ; Vol. 887, No. 2. pp. 418-420.
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