Alcohol Consumption and Coronary Artery Calcium in Middle-Aged Japanese Men

Tomonori Okamura, Takashi Kadowaki, Akira Sekikawa, Kiyoshi Murata, Naomi Miyamatsu, Yasuyuki Nakamura, Aiman El-Saed, Atsunori Kashiwagi, Hiroshi Maegawa, Yoshihiko Nishio, Tomoko Takamiya, Hideyuki Kanda, Kenichi Mitsunami, Yoshikuni Kita, Daniel Edmundowicz, Shinji Tamaki, Yasuyuki Tsujita, Lewis H. Kuller, Hirotsugu Ueshima

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Abstract

Epidemiologic studies have investigated the relation between alcohol intake and coronary calcification, with controversial results. Furthermore, the influence of heavy drinking has not been well elucidated. In the present study, a random sample of community-based Japanese men aged 40 to 49 years without a history of cardiovascular disease (n = 245) were examined for coronary artery calcium (CAC) determined by electron-beam computed tomography and drinking status. There was a J-shaped association between alcohol intake and CAC. There was an increase of CAC in heavy drinkers (≥46 g/day), and participants who were drinking ≥69 g/day showed a significant increase in CAC compared with never drinkers after adjusting for other cardiovascular risk factors.

Original languageEnglish
Pages (from-to)141-144
Number of pages4
JournalAmerican Journal of Cardiology
Volume98
Issue number2
DOIs
Publication statusPublished - 2006 Jul 15

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ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Okamura, T., Kadowaki, T., Sekikawa, A., Murata, K., Miyamatsu, N., Nakamura, Y., El-Saed, A., Kashiwagi, A., Maegawa, H., Nishio, Y., Takamiya, T., Kanda, H., Mitsunami, K., Kita, Y., Edmundowicz, D., Tamaki, S., Tsujita, Y., Kuller, L. H., & Ueshima, H. (2006). Alcohol Consumption and Coronary Artery Calcium in Middle-Aged Japanese Men. American Journal of Cardiology, 98(2), 141-144. https://doi.org/10.1016/j.amjcard.2006.01.095