Alterations in gastric mucosal microvascular endothelium in a stressed condition--relevance to gastric ulcerogenesis.

M. Oda, M. Nakamura, K. Honda, H. Komatsu, K. Kaneko, T. Azuma, M. Suematsu, Y. Yonei, N. Watanabe, M. Tsuchiya

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The present paper describes the morphological and functional alterations of the gastric mucosal microvascular endothelium under restraint-stressed condition. On the basis of the direct cholinergic innervation of capillaries and non-muscular venules in the gastric mucosa, these endothelial changes would be caused by the stress-induced overstimulation of the cholinergic nerves and modified by the degranulation of mast cells, contributing to the stress-induced ulcer formation as schematically illustrated in Fig. 10.

Original languageEnglish
Pages (from-to)161-175
Number of pages15
JournalAdvances in Experimental Medicine and Biology
Volume242
Publication statusPublished - 1988

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Cholinergic Agents
Endothelium
Stomach
Venules
Gastric Mucosa
Mast Cells
Ulcer
Mucous Membrane

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Oda, M., Nakamura, M., Honda, K., Komatsu, H., Kaneko, K., Azuma, T., ... Tsuchiya, M. (1988). Alterations in gastric mucosal microvascular endothelium in a stressed condition--relevance to gastric ulcerogenesis. Advances in Experimental Medicine and Biology, 242, 161-175.

Alterations in gastric mucosal microvascular endothelium in a stressed condition--relevance to gastric ulcerogenesis. / Oda, M.; Nakamura, M.; Honda, K.; Komatsu, H.; Kaneko, K.; Azuma, T.; Suematsu, M.; Yonei, Y.; Watanabe, N.; Tsuchiya, M.

In: Advances in Experimental Medicine and Biology, Vol. 242, 1988, p. 161-175.

Research output: Contribution to journalArticle

Oda, M, Nakamura, M, Honda, K, Komatsu, H, Kaneko, K, Azuma, T, Suematsu, M, Yonei, Y, Watanabe, N & Tsuchiya, M 1988, 'Alterations in gastric mucosal microvascular endothelium in a stressed condition--relevance to gastric ulcerogenesis.', Advances in Experimental Medicine and Biology, vol. 242, pp. 161-175.
Oda, M. ; Nakamura, M. ; Honda, K. ; Komatsu, H. ; Kaneko, K. ; Azuma, T. ; Suematsu, M. ; Yonei, Y. ; Watanabe, N. ; Tsuchiya, M. / Alterations in gastric mucosal microvascular endothelium in a stressed condition--relevance to gastric ulcerogenesis. In: Advances in Experimental Medicine and Biology. 1988 ; Vol. 242. pp. 161-175.
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