Alterations in gastric mucosal microvascular endothelium in a stressed condition--relevance to gastric ulcerogenesis.

M. Oda, M. Nakamura, K. Honda, H. Komatsu, K. Kaneko, T. Azuma, M. Suematsu, Y. Yonei, N. Watanabe, M. Tsuchiya

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

The present paper describes the morphological and functional alterations of the gastric mucosal microvascular endothelium under restraint-stressed condition. On the basis of the direct cholinergic innervation of capillaries and non-muscular venules in the gastric mucosa, these endothelial changes would be caused by the stress-induced overstimulation of the cholinergic nerves and modified by the degranulation of mast cells, contributing to the stress-induced ulcer formation as schematically illustrated in Fig. 10.

Original languageEnglish
Pages (from-to)161-175
Number of pages15
JournalAdvances in experimental medicine and biology
Volume242
DOIs
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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