Amine-free silylation of alcohols under 4-methylpyridine N-oxide-catalyzed conditions

Keisuke Yoshida, Yuta Fujino, Yukihiro Itatsu, Hiroki Inoue, Yohei Kanoko, Kenichi Takao

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6 Citations (Scopus)

Abstract

Amine-free silylation of various alcohols catalyzed by 4-methylpyridine N-oxide in the presence of MS4A at room temperature was developed. This simple method gave various silyl ethers in a high yield.

Original languageEnglish
Pages (from-to)627-631
Number of pages5
JournalTetrahedron Letters
Volume57
Issue number5
DOIs
Publication statusPublished - 2016 Feb 3

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Keywords

  • 4-Methylpyridine N-oxide
  • Amine-free
  • MS4A
  • Silylation

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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